Evidence map›Paper›PMID 39057625›Full record

ArticleJournal of cardiovascular development and disease2024

Association of Abnormal Cardiac Biomarkers and Cardiovascular Complications, with Mortality in Patients with SARS-CoV-2 Infection in Latin America.

Juan Esteban Gómez-Mesa, Manuela Escalante, Juan Andrés Muñoz-Ordoñez, Valeria Azcárate-Rodriguez, Juan David Peláez-Martínez, Andrea Alejandra Arteaga-Tobar, Hoover León-Giraldo, Andrea Valencia-Orozco, Eduardo Roque Perna, Alexander Romero and 11 more

Abstract read
In one paragraph

Article in Journal of cardiovascular development and disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Juan Esteban Gómez-MesaDepartamento de Cardiología, Fundación Valle del Lili, Cali 760032, Colombia.ORCID 0000-0002-6635-6224
Manuela EscalanteFacultad de Ciencias de Salud, Universidad Icesi, Cali 760031, Colombia.
Juan Andrés Muñoz-OrdoñezFacultad de Ciencias de Salud, Universidad Icesi, Cali 760031, Colombia.ORCID 0009-0009-1278-8943
Valeria Azcárate-RodriguezFacultad de Ciencias de Salud, Universidad Icesi, Cali 760031, Colombia.ORCID 0009-0007-8219-9285
Juan David Peláez-MartínezFacultad de Ciencias de Salud, Universidad Icesi, Cali 760031, Colombia.ORCID 0000-0003-0032-6417
Andrea Alejandra Arteaga-TobarDepartamento de Cardiología, Fundación Valle del Lili, Cali 760032, Colombia.ORCID 0009-0008-5490-2794
Hoover León-GiraldoCentro de Investigaciones Clínicas, Fundación Valle del Lili, Cali 760032, Colombia.ORCID 0000-0002-8854-105X
Andrea Valencia-OrozcoCentro de Investigaciones Clínicas, Fundación Valle del Lili, Cali 760032, Colombia.
Eduardo Roque PernaDepartamento de Cardiología, Instituto de Cardiología JF Cabral, Corrientes 3400, Argentina.ORCID 0000-0002-9977-7623
Alexander RomeroDepartamento de Cardiología, Hospital Santo Tomas, Panama City 07093, Panama.
Iván MendozaDepartamento de Cardiología, Universidad Central de Venezuela, Caracas 1040A, Venezuela.ORCID 0000-0002-9098-8424
Fernando WyssDepartamento de Cardiología, Servicios y Tecnología Cardiovascular de Guatemala S.A-Cardiosolutions, Guatemala City 01010, Guatemala.ORCID 0000-0003-1700-4692
José Luis BarisaniDepartamento de Cardiología, Clínica Adventista Belgrano, Buenos Aires 1710, Argentina.ORCID 0000-0002-2206-8466
Mario SperanzaDepartamento de Cardiología, Hospital Clínica Bíblica, San Jose 10104, Costa Rica.ORCID 0000-0002-6947-0735
Walter AlarcoDepartamento de Cardiología, Instituto Nacional Cardiovascular INCOR ESSALUD, Lima 15072, Peru.ORCID 0000-0001-5881-4080
Cesar HerreraDepartamento de Cardiología, Centro de Diagnóstico, Medicina Avanzada y Telemedicina (CEDIMAT), Santo Domingo 10216, Dominican Republic.
Julián Lugo-PeñaDepartamento de Cardiología, Clínica del Occidente, Bogota 110110, Colombia.ORCID 0000-0002-5867-2876
Liliana Patricia Cárdenas-AldazDepartamento de Cardiología, Hospital Eugenio Espejo, Quito 170136, Ecuador.
Victor RosselDepartamento de Cardiología, Hospital del Salvador, San Salvador 1101, El Salvador.ORCID 0000-0002-4212-1148
Daniel SierraDepartamento de Cardiología, Instituto Nacional de Cardiología-Ignacio Chávez, Mexico City 14080, Mexico.
CARDIO COVID 19-20 Research Team

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe COVID-19 pandemic has highlighted a correlation between cardiac complications and elevated cardiac biomarkers, which are linked to poorer clinical outcomes.

objectiveThis study aims to determine the clinical impact of cardiac biomarkers in COVID-19 patients in Latin America. SUBJECTS AND

methodsThe CARDIO COVID 19-20 Registry is a multicenter observational study across 44 hospitals in Latin America and the Caribbean. It included hospitalized COVID-19 patients (

resultsAmong the 476 patients tested, 139 had one positive biomarker (Group C), 190 had two (Group B), 118 had three (Group A), and 29 had none (Group D). A directly proportional relationship was observed between the number of positive biomarkers and the incidence of decompensated heart failure. Similarly, there was a proportional relationship between the number of positive biomarkers and increased mortality. In Group B, patients with elevated troponin and natriuretic peptide and those with elevated troponin and D-dimer had 1.4 and 1.5 times higher mortality, respectively, than those with elevated natriuretic peptide and D-dimer.

conclusionsIn Latin American COVID-19 patients, a higher number of positive cardiac biomarkers is associated with increased cardiovascular complications and mortality. These findings suggest that cardiac biomarkers should be utilized to guide acute-phase treatment strategies.

Indexed as

biomarkerscardiovascular diseaseCOVID-19mortalityprognosisSARS-CoV-2

Identifiers

PMID39057625
PMCPMC11277850

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.