Evidence map›Paper›PMID 39060016›Full record

Observational studyThe European respiratory journal2024

Chronic thromboembolic pulmonary hypertension is an uncommon complication of COVID-19: UK national surveillance and observational screening cohort studies.

S Ashwin Reddy, Joseph Newman, Olivia C Leavy, Hakim Ghani, Joanna Pepke-Zaba, John E Cannon, Karen K Sheares, Dolores Taboada, Katherine Bunclark, Allan Lawrie and 25 more

Erratum issuedAbstract readObservational StudyMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in The European respiratory journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

35 authors.

S Ashwin ReddyRoyal Papworth Hospital NHS Foundation Trust, Cambridge, UK.ORCID https://orcid.org/0000-0001-7510-1189
Joseph NewmanRoyal Papworth Hospital NHS Foundation Trust, Cambridge, UK.ORCID https://orcid.org/0000-0001-5514-0754
Olivia C LeavyUniversity of Leicester, Leicester, UK.
Hakim GhaniRoyal Papworth Hospital NHS Foundation Trust, Cambridge, UK.
Joanna Pepke-ZabaRoyal Papworth Hospital NHS Foundation Trust, Cambridge, UK.
John E CannonRoyal Papworth Hospital NHS Foundation Trust, Cambridge, UK.
Karen K ShearesRoyal Papworth Hospital NHS Foundation Trust, Cambridge, UK.
Dolores TaboadaRoyal Papworth Hospital NHS Foundation Trust, Cambridge, UK.
Katherine BunclarkRoyal Papworth Hospital NHS Foundation Trust, Cambridge, UK.
Allan LawrieSheffield Teaching NHS Foundation Trust and University of Sheffield, Sheffield, UK.ORCID https://orcid.org/0000-0003-4192-9505
Cathie L SudlowUniversity of Edinburgh, Edinburgh, UK.
Colin BerryNHS Greater Glasgow and Clyde Health Board, and University of Glasgow, Glasgow, UK.
James M WildSheffield Teaching NHS Foundation Trust and University of Sheffield, Sheffield, UK.
Jane A MitchellImperial College London, London, UK.
Jennifer QuintImperial College London, London, UK.ORCID https://orcid.org/0000-0003-0149-4869
Jennifer RossdaleGuy's and St Thomas' NHS Foundation Trust, London, UK.
Laura PriceImperial College London, London, UK.ORCID https://orcid.org/0000-0001-5250-660X
Luke S HowardImperial College London, London, UK.ORCID https://orcid.org/0000-0003-2822-210X
Martin WilkinsImperial College London, London, UK.ORCID https://orcid.org/0000-0003-3926-1171
Naveed SattarNHS Greater Glasgow and Clyde Health Board, and University of Glasgow, Glasgow, UK.
Philip ChowienczykRoyal Brompton Hospital, London, UK.
Roger ThompsonSheffield Teaching NHS Foundation Trust and University of Sheffield, Sheffield, UK.ORCID https://orcid.org/0000-0002-0717-4551
Louise V WainNIHR Leicester Biomedical Research Centre, The Institute for Lung Health, University of Leicester, Leicester, UK.ORCID https://orcid.org/0000-0003-4951-1867
Alexander HorsleyManchester University NHS Foundation Trust and University of Manchester, Manchester, UK.ORCID https://orcid.org/0000-0003-1828-0058
Ling-Pei HoUniversity of Oxford, Oxford, UK.
James D ChalmersNHS Tayside and University of Dundee, Dundee, UK.
Michael MarksLondon School of Hygiene and Tropical Medicine, London, UK.ORCID https://orcid.org/0000-0002-7585-4743
Krisnah PoinasamyAsthma UK and British Lung Foundation Partnership, London, UK.
Betty RamanUniversity of Oxford, Oxford, UK.ORCID https://orcid.org/0000-0002-1239-9608
Victoria C HarrisUniversity of Leicester, Leicester, UK.
Linzy Houchen-WolloffUniversity of Leicester, Leicester, UK.
Christopher E BrightlingNIHR Leicester Biomedical Research Centre, The Institute for Lung Health, University of Leicester, Leicester, UK.
Rachael A EvansNIHR Leicester Biomedical Research Centre, The Institute for Lung Health, University of Leicester, Leicester, UK.ORCID https://orcid.org/0000-0002-1667-868X
Mark R ToshnerRoyal Papworth Hospital NHS Foundation Trust, Cambridge, UK mrt34@medschl.cam.ac.uk.ORCID https://orcid.org/0000-0002-3969-6143
PHOSP-COVID Study Collaborative Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPulmonary embolism (PE) is a well-recognised complication of coronavirus disease 2019 (COVID-19) infection, and chronic thromboembolic pulmonary disease with and without pulmonary hypertension (CTEPD/CTEPH) are potential life-limiting consequences. At present the burden of CTEPD/CTEPH is unclear and optimal and cost-effective screening strategies yet to be established.

methodsWe evaluated the CTEPD/CTEPH referral rate to the UK national multidisciplinary team (MDT) during the 2017-2022 period to establish the national incidence of CTEPD/CTEPH potentially attributable to COVID-19-associated PE with historical comparator years. All individual cases of suspected CTEPH were reviewed by the MDT for evidence of associated COVID-19. In a separate multicentre cohort, the risk of developing CTEPH following hospitalisation with COVID-19 was calculated using simple clinical parameters at a median of 5 months post-hospital discharge according to existing risk scores using symptoms, ECG and N-terminal pro-brain natriuretic peptide.

resultsBy the second year of the pandemic, CTEPH diagnoses had returned to the pre-pandemic baseline (23.1

conclusion

Indexed as

COVID-19Hypertension, PulmonaryPulmonary EmbolismAdultAgedChronic DiseaseCohort StudiesFemaleHospitalizationHumansIncidenceMaleMiddle AgedSARS-CoV-2United Kingdom

Identifiers

PMID39060016
PMCPMC11358513

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.