Evidence map›Paper›PMID 39061670›Full record

ArticleDiagnostics (Basel, Switzerland)2024

Aneurysmal Wall Enhancement of Non-Ruptured Intracranial Aneurysms after Endovascular Treatment Correlates with Higher Aneurysm Reperfusion Rates, but Only in Large Aneurysms.

Valentin Ladenhauf, Malik Galijasevic, Milovan Regodic, Raimund Helbok, Verena Rass, Christian Freyschlag, Ondra Petr, Johannes Deeg, Leonhard Gruber, Stephanie Mangesius and 2 more

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Valentin LadenhaufDepartment of Radiology, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Malik GalijasevicDepartment of Radiology, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0001-6577-0784
Milovan RegodicNeuroimaging Research Core Facility, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.ORCID 0000-0002-8244-9287
Raimund HelbokDepartment of Neurology, Kepler University Hospital, Johannes Kepler University Linz, 4020 Linz, Austria.
Verena RassDepartment of Neurology, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Christian FreyschlagDepartment of Neurosurgery, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0002-8228-8217
Ondra PetrDepartment of Neurosurgery, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Johannes DeegDepartment of Radiology, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0002-5139-4287
Leonhard GruberDepartment of Radiology, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Stephanie MangesiusDepartment of Radiology, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0001-5790-2724
Elke Ruth GizewskiDepartment of Radiology, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0001-6859-8377
Astrid Ellen GramsDepartment of Radiology, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0003-2304-3946

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAneurysmal wall enhancement (AWE) of non-ruptured sacular intracranial aneurysms (IA) after endovascular treatment (ET) is a frequently observed imaging finding using AWE-sequences in brain magnetic resonance imaging (MRI). So far, its value remains unclear. We aimed to investigate the effect of AWE on aneurysm reperfusion rates in a longitudinal cohort.

methodsThis is a retrospective MRI study over the timespan of up to 5 years, assessing the correlation of increased AWE of non-ruptured IAs and events of aneurysm reperfusion and retreatment, PHASES Score and grade of AWE. T1 SPACE fat saturation (FS) and T1 SE FS blood suppression sequences after contrast administration were used for visual interpretation of increased AWE. The IAs' sizes were assessed via the biggest diameter. The grade of enhancement was defined in a grading system from grade 1 to grade 3.

results127 consecutive non ruptured IA-patients (58.9 ± 9.0 years, 94 female, 33 male) who underwent elective aneurysm occlusion were included. AWE was observed in 40.2% of patients (51/127) after ET, 6 patients already showed AWE before treatment. In large IAs (which were defined as a single maximum diameter of over 7.5 mm), AWE was significantly associated with aneurysm reperfusion in contrast to large aneurysm without AWE). All grades of AWE were significantly associated with reperfusion.

conclusionsOur data suggests that in patients with initially large IAs, AWE is correlated with aneurysm reperfusion.

Indexed as

aneurysmMRIneuroradiologyreperfusion

Identifiers

PMID39061670
PMCPMC11276124

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.