Evidence map›Paper›PMID 39062113›Full record

ReviewBiomedicines2024

Role of ncRNAs in the Pathogenesis of Sjögren's Syndrome.

Amal Al-Haidose, Sondoss Hassan, Mahmoud Elhassan, Eiman Ahmed, Abdulla Al-Riashi, Yazeed M Alharbi, Monther Ghunaim, Talal Alhejaili, Atiyeh M Abdallah

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Biomedicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Amal Al-HaidoseDepartment of Biomedical Sciences, College of Health Sciences, QU Health, Qatar University, Doha 2713, Qatar.ORCID 0009-0000-8705-0198
Sondoss HassanDepartment of Biomedical Sciences, College of Health Sciences, QU Health, Qatar University, Doha 2713, Qatar.ORCID 0009-0008-6666-9619
Mahmoud ElhassanDepartment of Biomedical Sciences, College of Health Sciences, QU Health, Qatar University, Doha 2713, Qatar.
Eiman AhmedDepartment of Biomedical Sciences, College of Health Sciences, QU Health, Qatar University, Doha 2713, Qatar.
Abdulla Al-RiashiDepartment of Biomedical Sciences, College of Health Sciences, QU Health, Qatar University, Doha 2713, Qatar.
Yazeed M AlharbiDepartment of Internal Medicine, Collage of Medicine, Taibah University, Madinah 42353, Saudi Arabia.
Monther GhunaimDepartment of Internal Medicine, Collage of Medicine, Taibah University, Madinah 42353, Saudi Arabia.
Talal AlhejailiDepartment of Gastroenterology, King Salman Medical City, Madinah 42319, Saudi Arabia.ORCID 0009-0007-4025-9980
Atiyeh M AbdallahDepartment of Biomedical Sciences, College of Health Sciences, QU Health, Qatar University, Doha 2713, Qatar.ORCID 0000-0003-4812-956X

Funding

qatar university QUCP-CHS-2022-551
6 · The paper itself

Abstract

Sjögren's syndrome is a multisystemic autoimmune disease that mainly affects the exocrine glands, causing dryness of the eyes and the mouth as the principal symptoms. Non-coding RNAs (ncRNAs), once regarded as genomic "junk", are now appreciated as important molecular regulators of gene expression, not least in Sjögren's syndrome and other autoimmune diseases. Here we review research into the causative roles of microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs) on immunological responses, inflammation, and salivary gland epithelial cell function in Sjögren's syndrome patients. These ncRNAs represent promising new therapeutic targets for treating the disease and possibly as biomarkers for early diagnosis.

Indexed as

autoimmune diseasenon-coding RNAsRNA expressionSjögren’s syndrome

Identifiers

PMID39062113
PMCPMC11274537

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.