Evidence mapPaperPMID 39062503Full record

ReviewBiomolecules2024

Alginate-Based Electrospun Nanofibers and the Enabled Drug Controlled Release Profiles: A Review.

Zhiyuan Zhang, Hui Liu, Deng-Guang Yu, Sim-Wan Annie Bligh

Abstract readReview
In one paragraph

Review in Biomolecules, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Versatility of electrospun Janus wound dressings.Nanomedicine (London, England) · 2025
    Review
  14. Review
  15. Review
  16. Electrospun nanofibers and their application as sensors for healthcare.Frontiers in bioengineering and biotechnology · 2025
    Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zhiyuan ZhangSchool of Materials and Chemistry, University of Shanghai for Science and Technology, Shanghai 200093, China.
Hui LiuSchool of Materials and Chemistry, University of Shanghai for Science and Technology, Shanghai 200093, China.
Deng-Guang YuSchool of Materials and Chemistry, University of Shanghai for Science and Technology, Shanghai 200093, China.ORCID 0000-0001-7825-4498
Sim-Wan Annie BlighSchool of Health Sciences, Saint Francis University, Hong Kong 999077, China.ORCID 0000-0002-4757-2159

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alginate is a natural polymer with good biocompatible properties and is a potential polymeric material for the sustainable development and replacement of petroleum derivatives. However, the non-spinnability of pure alginate solutions has hindered the expansion of alginate applications. With the continuous development of electrospinning technology, synthetic polymers, such as PEO and PVA, are used as co-spinning agents to increase the spinnability of alginate. Moreover, the coaxial, parallel Janus, tertiary and other diverse and novel electrospun fiber structures prepared by multi-fluid electrospinning have found a new breakthrough for the problem of poor spinning of natural polymers. Meanwhile, the diverse electrospun fiber structures effectively achieve multiple release modes of drugs. The powerful combination of alginate and electrostatic spinning is widely used in many biomedical fields, such as tissue engineering, regenerative engineering, bioscaffolds, and drug delivery, and the research fever continues to climb. This is particularly true for the controlled delivery aspect of drugs. This review provides a brief overview of alginate, introduces new advances in electrostatic spinning, and highlights the research progress of alginate-based electrospun nanofibers in achieving various controlled release modes, such as pulsed release, sustained release, biphasic release, responsive release, and targeted release.

Indexed as

AlginatesDelayed-Action PreparationsNanofibersAnimalsDrug CarriersDrug Delivery SystemsDrug LiberationHumansTissue EngineeringAlginatesDelayed-Action PreparationsDrug Carriersalginatebiomedicalcontrolled releasedrug deliveryelectrospinningnanostructure

Identifiers

PMID39062503
PMCPMC11274620

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.