Evidence map›Paper›PMID 39062630›Full record

ArticleGenes2024

Studies on Human Cultured Fibroblasts and Cutaneous Squamous Cell Carcinomas Suggest That Overexpression of Histone Variant H2A.J Promotes Radioresistance and Oncogenic Transformation.

Benjamin M Freyter, Mutaz A Abd Al-Razaq, Markus Hecht, Christian Rübe, Claudia E Rübe

Abstract read
In one paragraph

Article in Genes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Benjamin M FreyterDepartment of Radiation Oncology, Saarland University Medical Center, 66421 Homburg, Germany.
Mutaz A Abd Al-RazaqDepartment of Radiation Oncology, Saarland University Medical Center, 66421 Homburg, Germany.ORCID 0009-0009-4291-8964
Markus HechtDepartment of Radiation Oncology, Saarland University Medical Center, 66421 Homburg, Germany.ORCID 0000-0003-2082-216X
Christian RübeDepartment of Radiation Oncology, Saarland University Medical Center, 66421 Homburg, Germany.
Claudia E RübeDepartment of Radiation Oncology, Saarland University Medical Center, 66421 Homburg, Germany.ORCID 0000-0003-3882-7903

Funding

Federal Ministry of Education and Research (BMBF) 02NUK058BGerman Cancer Aid (Deutsche Krebshilfe) 70113135German Research Foundation (Deutsche Forschungsgemein-schaft) RU821/8-1
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Carcinoma, Squamous CellCell Transformation, NeoplasticCellular SenescenceFibroblastsHistonesSkin NeoplasmsCells, CulturedEpigenesis, GeneticGene Expression Regulation, NeoplasticHumansRadiation, IonizingRadiation ToleranceHistoneshistone variant H2A.Jionizing radiationoncogenic transformationradiation-induced senescenceradioresistancesenescence-associated heterochromatin foci (SAHF)WNT signaling

Identifiers

PMID39062630
PMCPMC11275829

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.