Evidence mapPaperPMID 39063142Full record

ReviewInternational journal of molecular sciences2024

The Link between Inflammation, Lipid Derivatives, and Microbiota Metabolites in COVID-19 Patients: Implications on Eating Behaviors and Nutritional Status.

Viktoria Hawryłkowicz, Beata Stasiewicz, Dominika Maciejewska, Joanna Sołek-Pastuszka, Natalia Komorniak, Karolina Skonieczna-Żydecka, Alexandra Martynova-Van Kley, Ewa Stachowska

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Viktoria HawryłkowiczDepartment of Human Nutrition and Metabolomics, Pomeranian Medical University, 71-460 Szczecin, Poland.
Beata StasiewiczDepartment of Human Nutrition, The Faculty of Food Science, University of Warmia and Mazury in Olsztyn, Sloneczna 45f, 10-718 Olsztyn, Poland.ORCID 0000-0003-0718-9101
Dominika MaciejewskaDepartment of Human Nutrition and Metabolomics, Pomeranian Medical University, 71-460 Szczecin, Poland.ORCID 0000-0002-2293-6489
Joanna Sołek-PastuszkaDepartment of Anesthesiology and Intensive Care, Pomeranian Medical University, 71-242 Szczecin, Poland.
Natalia KomorniakDepartment of Human Nutrition and Metabolomics, Pomeranian Medical University, 71-460 Szczecin, Poland.ORCID 0000-0002-4318-1513
Karolina Skonieczna-ŻydeckaDepartment of Biochemical Sciences, Pomeranian Medical University, 71-460 Szczecin, Poland.
Alexandra Martynova-Van KleyDepartment of Biology, Stephen F. Austin State University at UT, Nacogdoches, TX 75962, USA.
Ewa StachowskaDepartment of Human Nutrition and Metabolomics, Pomeranian Medical University, 71-460 Szczecin, Poland.ORCID 0000-0002-4009-1977

Funding

This research was funded by the Pomeranian Medical University in Szczecin, Poland (Project number: WNoZ 330-05/S/2024).
6 · The paper itself

Abstract

Extreme inflammation that continues even after infections can lead to a cytokine storm. In recent times, one of the most common causes of cytokine storm activation has been SARS-CoV-2 infection. A cytokine storm leads to dysregulation and excessive stimulation of the immune system, producing symptoms typical of post-COVID syndrome, including chronic fatigue, shortness of breath, joint pain, trouble concentrating (known as "brain fog"), and even direct organ damage in the heart, lungs, kidneys, and brain. This work summarizes the current knowledge regarding inflammation and the cytokine storm related to SARS-CoV-2 infection. Additionally, changes in lipid metabolism and microbiota composition under the influence of inflammation in COVID-19, along with the possible underlying mechanisms, are described. Finally, this text explores potential health implications related to changes in eating behaviors and nutritional status in COVID-19 patients. Although research on the cytokine storm is still ongoing, there is convincing evidence suggesting that severe immune and inflammatory responses during the acute phase of COVID-19 may lead to long-term health consequences. Understanding these links is key to developing treatment strategies and supporting patients after infection.

Indexed as

COVID-19Cytokine Release SyndromeFeeding BehaviorInflammationLipid MetabolismNutritional StatusSARS-CoV-2Gastrointestinal MicrobiomeHumansMicrobiotaCOVID-19cytokinelipidsmetabolitesmicrobiotanutritionSARS-CoV-2

Identifiers

PMID39063142
PMCPMC11276903

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.