Evidence map›Paper›PMID 39063149›Full record

ArticleInternational journal of molecular sciences2024

Exploiting

Luca Frattaruolo, Graziantonio Lauria, Francesca Aiello, Gabriele Carullo, Rosita Curcio, Marco Fiorillo, Giuseppe Campiani, Vincenza Dolce, Anna Rita Cappello

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Molecules (Basel, Switzerland) · 2025
    Article
  3. Special Issue "Mitochondrial Metabolism Alterations in Health and Disease".International journal of molecular sciences · 2025
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Luca FrattaruoloDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, Via P. Bucci, 87036 Rende, CS, Italy.ORCID 0000-0002-7018-8454
Graziantonio LauriaDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, Via P. Bucci, 87036 Rende, CS, Italy.ORCID 0000-0002-6676-0585
Francesca AielloDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, Via P. Bucci, 87036 Rende, CS, Italy.ORCID 0000-0001-6846-5582
Gabriele CarulloDepartment of Biotechnology, Chemistry and Pharmacy, University of Siena, Via A. Moro 2, 53100 Siena, SI, Italy.ORCID 0000-0002-1619-3295
Rosita CurcioDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, Via P. Bucci, 87036 Rende, CS, Italy.ORCID 0000-0002-4077-0101
Marco FiorilloDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, Via P. Bucci, 87036 Rende, CS, Italy.ORCID 0000-0002-8055-3259
Giuseppe CampianiDepartment of Biotechnology, Chemistry and Pharmacy, University of Siena, Via A. Moro 2, 53100 Siena, SI, Italy.
Vincenza DolceDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, Via P. Bucci, 87036 Rende, CS, Italy.ORCID 0000-0003-2966-4866
Anna Rita CappelloDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, Via P. Bucci, 87036 Rende, CS, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Research on the energy metabolism of cancer cells is becoming a central element in oncology, and in recent decades, it has allowed us to better understand the mechanisms underlying the onset and chemoresistance of oncological pathologies. Mitochondrial bioenergetic processes, in particular, have proven to be fundamental for the survival of tumor stem cells (CSC), a subpopulation of tumor cells responsible for tumor recurrence, the onset of metastasis, and the failure of conventional anticancer therapies. Over the years, numerous natural products, in particular flavonoids, widely distributed in the plant kingdom, have been shown to interfere with tumor bioenergetics, demonstrating promising antitumor effects. Herein, the anticancer potential of Licoflavanone, a flavanone isolated from the leaves of

Indexed as

Breast NeoplasmsEnergy MetabolismFlavanonesGlycyrrhizaAntineoplastic Agents, PhytogenicCell Line, TumorCell ProliferationFemaleHumansMCF-7 CellsNeoplastic Stem CellsPlant ExtractsAntineoplastic Agents, PhytogenicFlavanonesPlant Extractsanticancer agentsbreast cancercancer stem cellsenergy metabolismflavanonesLicoflavanonelicorice

Identifiers

PMID39063149
PMCPMC11276871

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.