Evidence map›Paper›PMID 39063199›Full record

Trial reportInternational journal of molecular sciences2024

The Biological Effect of Platelet-Rich Plasma on Rotator Cuff Tears: A Prospective Randomized In Vivo Study.

Charalampos Pitsilos, Sofia Karachrysafi, Aikaterini Fragou, Ioannis Gigis, Pericles Papadopoulos, Byron Chalidis

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Platelet Products and Artificial Platelets for Regenerative Medicine.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2026
    Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Charalampos Pitsilos2nd Orthopaedic Department, Aristotle University of Thessaloniki, 54635 Thessaloniki, Greece.ORCID 0000-0002-3091-866X
Sofia KarachrysafiResearch Team "Histologistas", Interinstitutional Postgraduate Program "Health and Environmental Factors", Department of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0001-6309-8410
Aikaterini FragouLaboratory of Biological Chemistry, Medical Department, School of Health Science, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0002-3443-6908
Ioannis Gigis2nd Orthopaedic Department, Aristotle University of Thessaloniki, 54635 Thessaloniki, Greece.ORCID 0000-0002-4214-9036
Pericles Papadopoulos2nd Orthopaedic Department, Aristotle University of Thessaloniki, 54635 Thessaloniki, Greece.
Byron Chalidis1st Orthopaedic Department, Aristotle University of Thessaloniki, 57010 Thessaloniki, Greece.ORCID 0000-0003-1305-2734

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The positive effect of platelet-rich plasma (PRP) on tendon metabolism has been extensively investigated and proven in vitro. Additionally, in vivo animal studies have correlated the application of PRP with the enhancement of tenocyte anabolic activity in the setting of tendon degeneration. However, less is known about its in vivo effect on human tendon biology. The purpose of the current prospective randomized comparative study was to evaluate the effect of PRP on torn human supraspinatus tendon. Twenty consecutive eligible patients with painful and magnetic resonance imaging (MRI)-confirmed degenerative supraspinatus tendon tears were randomized in a one-to-one ratio into two groups. The patients in the experimental group (

Indexed as

Platelet-Rich PlasmaRotator Cuff InjuriesAdultAgedFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedProspective StudiesRotator Cuffcollagenfibroblasthistologymicroscopyplatelet-rich plasmarotator cufftendon

Identifiers

PMID39063199
PMCPMC11277466

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.