Evidence map›Paper›PMID 39063214›Full record

ArticleInternational journal of molecular sciences2024

Discovery of the Natural Bibenzyl Compound Erianin in Dendrobium Inhibiting the Growth and EMT of Gastric Cancer through Downregulating the LKB1-SIK2/3-PARD3 Pathway.

Xin Wei, Qunshan Liu, Liu Liu, Dan Wang, Jiajia Liu, Qizhi Zhu, Ziming Xu, Qi Chen, Weiping Xu

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. [Erianin inhibits proliferation and migration of breast cancer cellsNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2026
    Article
  3. Article
  4. A Bibenzyl fromAntioxidants (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xin WeiInstitute of Intelligent Machines, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, China.
Qunshan LiuDivision of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230026, China.
Liu LiuDivision of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230026, China.
Dan WangDivision of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230026, China.
Jiajia LiuDivision of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230026, China.
Qizhi ZhuInstitute of Intelligent Machines, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, China.
Ziming XuDivision of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230026, China.
Qi ChenInstitute of Intelligent Machines, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, China.
Weiping XuInstitute of Intelligent Machines, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, China.

Funding

National Natural Science Foundation of China 52072360
6 · The paper itself

Abstract

Erianin, a bibenzyl compound found in dendrobium extract, has demonstrated broad anticancer activity. However, its mechanism of action in gastric cancer (GC) remains poorly understood.

Indexed as

AMP-Activated Protein Kinase KinasesBibenzylsCell ProliferationDendrobiumEpithelial-Mesenchymal TransitionProtein Serine-Threonine KinasesStomach NeoplasmsAnimalsApoptosisCell Line, TumorCell MovementDown-RegulationGene Expression Regulation, NeoplasticHumansMicePhenolAMP-Activated Protein Kinase KinasesBibenzylsErianinPhenolProtein Serine-Threonine KinasesSTK11 protein, human5-FUepithelial to mesenchymal transitionErianingastric cancerLKB1PARD3

Identifiers

PMID39063214
PMCPMC11277420

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.