Evidence map›Paper›PMID 39064690›Full record

SynthesisNutrients2024

Nutrition in Gilbert's Syndrome-A Systematic Review of Clinical Trials According to the PRISMA Statement.

Zuzanna Goluch, Aldona Wierzbicka-Rucińska, Ewelina Książek

Abstract readSystematic Review
In one paragraph

Synthesis in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zuzanna GoluchDepartment of Food Technology and Nutrition, Wroclaw University of Economics and Business, Komandorska 118/120, 53-345 Wrocław, Poland.ORCID 0000-0002-6241-3914
Aldona Wierzbicka-RucińskaDepartment of Clinical Biochemistry, Radioimmunology and Experimental Medicine, Children's Memorial Health Institute, 04-730 Warsaw, Poland.ORCID 0000-0002-9578-8894
Ewelina KsiążekDepartment of Agricultural Engineering and Quality Analysis, Wrocław University of Economics and Business, Komandorska 118/120, 53-345 Wrocław, Poland.ORCID 0000-0001-6416-0458

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gilbert syndrome is the most common hyperbilirubinemia, associated with a mutation in the UGT1A1 bilirubin gene, which produces an enzyme that conjugates bilirubin with glucuronic acid. Episodes of jaundice occurring in GS negatively affect patients' quality of life. This systematic review aimed to analyze clinical studies regarding nutrition in people with GS. The study followed the PRISMA guidelines and utilized the Ebsco, Embase, Cochrane, PubMed, Scopus, and Web of Science databases to search clinical trials focused on diet/nutrition in GS (1963-2023 years). The methodological quality of selected studies was assessed using the Jadad scale. As a result, 19 studies met the inclusion criteria. The research mainly focused on the impact of caloric restriction, consumption of various diet variants, and vegetables and fruits on hyperbilirubinemia and metabolic health. A nutritional intervention consisting of not applying excessive calorie restrictions and consuming fats and biologically active compounds in vegetables and fruits (

Indexed as

Gilbert DiseaseBilirubinCaloric RestrictionClinical Trials as TopicDietFruitGlucuronosyltransferaseHumansNutritional StatusQuality of LifeUGT1A1 EnzymeVegetablesBilirubinGlucuronosyltransferaseUGT1A1 Enzymecaloric restrictionsdietfastingGilbert diseaseGilbert syndromenutritionPRISMA

Identifiers

PMID39064690
PMCPMC11280271

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.