Evidence map›Paper›PMID 39064813›Full record

ArticleNutrients2024

Health-Promoting Potential of Mandarin Pomace Extracts Enriched with Phenolic Compounds.

Adriana Maite Fernández-Fernández, Eduardo Dellacassa, Romina Curbelo, Tiziana Nardin, Roberto Larcher, Alejandra Medrano-Fernandez, María Dolores Del Castillo

Abstract read
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Adriana Maite Fernández-FernándezDepartamento de Ciencia y Tecnología de Alimentos, Facultad de Química, Universidad de la República, General Flores 2124, Montevideo 11800, Uruguay.ORCID 0000-0003-4910-2318
Eduardo DellacassaDepartamento de Química Orgánica, Facultad de Química, Universidad de la República, General Flores 2124, Montevideo 11800, Uruguay.ORCID 0000-0002-4764-4212
Romina CurbeloDepartamento de Química Orgánica, Facultad de Química, Universidad de la República, General Flores 2124, Montevideo 11800, Uruguay.
Tiziana NardinDipartimento Alimenti e Trasformazione, Centro Trasferimento Tecnologico, Fondazione Edmund Mach di San Michele all'Adige, Via E. Mach, 1 38010 Trento, Italy.ORCID 0000-0001-7177-1062
Roberto LarcherDipartimento Alimenti e Trasformazione, Centro Trasferimento Tecnologico, Fondazione Edmund Mach di San Michele all'Adige, Via E. Mach, 1 38010 Trento, Italy.
Alejandra Medrano-FernandezDepartamento de Ciencia y Tecnología de Alimentos, Facultad de Química, Universidad de la República, General Flores 2124, Montevideo 11800, Uruguay.ORCID 0000-0002-5926-6239
María Dolores Del CastilloInstituto de Investigación en Ciencias de la Alimentación (CIAL) (CSIC-UAM), C/Nicolás Cabrera, 9, Campus de la Universidad Autónoma de Madrid, 28049 Madrid, Spain.ORCID 0000-0001-6309-5383

Funding

Agencia Nacional de Investigación e Innovación POS_NAC_2016_1_130292Consejo Superior de Investigaciones Científicas MHE-200003Ministerio de Ciencia, Innovación y Universidades PID2019- 111510RB-I00/AEI/10.13039/501100011033
6 · The paper itself

Abstract

The aim of this work was to assess the effect of in vitro human digestion on the chemical composition (carbohydrates and phenolic compounds) and bioactivity of hydro-alcoholic-acid pomace extracts from two mandarin varieties (Clemenule and Ortanique) by measuring their antioxidant, antidiabetic, anti-glycative, hypolipidemic, and anti-inflammatory properties. The phenolic compound profile showed that nobiletin was the main flavonoid found in the extracts and digests of Clemenule pomace and extract, while isosinensetin/sinensetin/tangeretin were the ones in the Ortanique samples. The digests of Clemenule and Ortanique extracts showed Folin reaction values of 9.74 and 9.20 mg gallic acid equivalents (GAE)/g of sample, ABTS values of 83.2 and 91.7 µmol Trolox equivalents (TE)/g of sample, and ORAC-FL values of 142.8 and 891.6 µmol TE/g of sample, respectively. Extracts (50-500 µg/mL) inhibited intracellular reactive oxygen species (ROS) formation in CCD-18Co cells under physiological and oxidative-induced conditions. Clemenule and Ortanique extract digests showed IC

Indexed as

Anti-Inflammatory AgentsAntioxidantsCitrusPhenolsPlant ExtractsAnimalsFlavonoidsFruitHumansHypoglycemic AgentsHypolipidemic AgentsMiceReactive Oxygen SpeciesAnti-Inflammatory AgentsAntioxidantsFlavonoidsHypoglycemic AgentsHypolipidemic AgentsPhenolsPlant ExtractsReactive Oxygen Speciesanti-inflammatoryantioxidantbioaccessibilitychronic diseasesflavonoidshydro-alcoholic-acid extractsmandarin pomacephenolic compoundsα-amylaseα-glucosidase

Identifiers

PMID39064813
PMCPMC11280356

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.