Evidence map›Paper›PMID 39065997›Full record

ArticleSensors (Basel, Switzerland)2024

Nanoimprinted Plasmonic Crystals for Cost-Effective SERS Identification of Methylated DNAs.

Daiki Kawasaki, Ryosuke Nishitsuji, Tatsuro Endo

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Daiki KawasakiMetamaterials Laboratory, RIKEN Cluster for Pioneering Research, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.
Ryosuke NishitsujiDepartment of Information Networking, Graduate School of Information Science and Technology, Osaka University, 2-8 Yamadaoka, Suita, Osaka 565-0871, Japan.
Tatsuro EndoDepartment of Applied Chemistry, Graduate School of Engineering, Osaka Metropolitan University, Sakai, Osaka 599-8531, Japan.ORCID 0000-0002-5704-5483

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of a cost-effective and rapid assay technique for the identification of DNA methylation is one of the most crucial issues in the field of biomedical diagnosis because DNA methylation plays key roles in human health. The plasmonic crystal-based surface-enhanced Raman spectroscopy (SERS) technique is promising for the realization of such an assay method owing to its capability of generating uniformly enhanced electric fields to achieve high reproducibility and accuracy in SERS assays. However, the time and technical costs of fabricating plasmonic crystals are high, owing to the need for nanofabrication equipment. In this study, we developed nanoimprinted plasmonic crystals for cost-effective and rapid DNA methylation assays. Our plasmonic crystals identified methylated DNA with the 40-base pair adenomatous polyposis coli (APC) gene sequence, which is correlated with cell growth and cancer cells.

Indexed as

DNADNA MethylationSpectrum Analysis, RamanCost-Benefit AnalysisHumansMetal NanoparticlesDNAAPC geneDNA methylationnanoimprint lithographyplasmonic crystalsSERS

Identifiers

PMID39065997
PMCPMC11280517

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.