Evidence map›Paper›PMID 39069640›Full record

ArticleInternational journal of stem cells2024

The Characterization and Regulation of Schwann Cells in the Tooth Germ Development and Odontogenic Differentiation.

Jing He, Ting Wang, Danyang Liu, Jun Yang, Yuanpei He, Shouliang Zhao, Yanqin Ju

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of stem cells, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jing HeDepartment of Stomatology, Huashan Hospital, Fudan University, Shanghai, China.ORCID https://orcid.org/0009-0001-5085-4915
Ting WangDepartment of Stomatology, Huashan Hospital, Fudan University, Shanghai, China.ORCID https://orcid.org/0009-0008-2183-4457
Danyang LiuDepartment of Stomatology, Huashan Hospital, Fudan University, Shanghai, China.ORCID https://orcid.org/0009-0008-8092-8170
Jun YangDepartment of Stomatology, Huashan Hospital, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0001-5445-0750
Yuanpei HeDepartment of Stomatology, Huashan Hospital, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0002-4168-4731
Shouliang ZhaoDepartment of Stomatology, Huashan Hospital, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0001-5960-9951
Yanqin JuDepartment of Stomatology, Huashan Hospital, Fudan University, Shanghai, China.ORCID https://orcid.org/0009-0001-0640-4124

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Schwann cells (SCs), a type of glial cell in the peripheral nervous system, can serve as a source of mesenchymal stem cells (MSCs) to repair injured pulp. This study aimed to investigate the role of SCs in tooth germ development and repair of pulp injury. We performed RNA-seq and immunofluorescent staining on tooth germs at different developmental stages. The effect of L-type calcium channel (LTCC) blocker nimodipine on SCs odontogenic differentiation was analyzed by real-time polymerase chain reaction and Alizarin Red S staining. We used the PLP1-CreERT2/ Rosa26-GFP tracing mice model to examine the role of SCs and Ca

Indexed as

CaOdontogenic differentiationPulp injuriesSchwann cellsTooth development

Identifiers

PMID39069640
PMCPMC11612224

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.