Evidence map›Paper›PMID 39070482›Full record

ArticleCureus2024

Unleashing the Cytokine Storm: A Case of Macrophage Activation Syndrome in Systemic Lupus Erythematosus.

Natalie Shaykh, Oshin Rai, Abhinav Karan, Khushman K Bhullar, Vanshika Tripathi, Pramod Reddy

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Natalie ShaykhInternal Medicine, University of Florida College of Medicine - Jacksonville, Jacksonville, USA.
Oshin RaiInternal Medicine, University of Florida College of Medicine - Jacksonville, Jacksonville, USA.
Abhinav KaranInternal Medicine, University of Florida College of Medicine - Jacksonville, Jacksonville, USA.
Khushman K BhullarInternal Medicine, Sri Guru Ram Das Institute of Medical Sciences and Research, Amritsar, IND.
Vanshika TripathiInternal Medicine, University of Florida College of Medicine - Jacksonville, Jacksonville, USA.
Pramod ReddyInternal Medicine, University of Florida College of Medicine - Jacksonville, Jacksonville, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Macrophage activation syndrome (MAS), synonymous with secondary hemophagocytic lymphohistiocytosis (HLH), is a rare and critical complication of rheumatologic disease stemming from the unregulated activation and rapid multiplication of macrophages and T lymphocytes. While it primarily manifests in children diagnosed with systemic juvenile idiopathic arthritis (sJIA), it can arise less frequently in other rheumatologic conditions. Here, we outline the clinical course, treatment, and outcome of MAS diagnosed in an 18-year-old female previously diagnosed with SLE who exhibited a unique clinical presentation.

Indexed as

cytokine storminghemophagocytic lymphohistiocytosis (hlh)macrophage activation syndrome (mas)steroid induced psychosissystemic lupus erythematosus with macrophage activation syndrome

Identifiers

PMID39070482
PMCPMC11272981

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.