ArticleCurrent opinion in behavioral sciences2024
Toward a computational role for locus coeruleus/norepinephrine arousal systems.
Article in Current opinion in behavioral sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed.
- Fluctuations in arousal reflect latent state transitions that facilitate behavioural optimization.Nature human behaviour · 2026Article
- Attenuated pupillary response during visual search in preclinical Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Phasic and tonic arousal distinctly shape human decision bias.Communications biology · 2026Article
- Hierarchical Reconfiguration of Neurocognitive Task Set Representations Mediates Cognitive Flexibility.bioRxiv : the preprint server for biology · 2026Article
- Article
- Locus coeruleus-related insula activation supports implicit learning.bioRxiv : the preprint server for biology · 2025Article
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
Brain and behavior undergo measurable changes in their underlying state and neuromodulators are thought to contribute to these fluctuations. Why do we undergo such changes, and what function could the underlying neuromodulatory systems perform? Here we examine theoretical answers to these questions with respect to the locus coeruleus/norepinephrine system focusing on peripheral markers for arousal, such as pupil diameter, that are thought to provide a window into brain wide noradrenergic signaling. We explore a computational role for arousal systems in facilitating internal state transitions that facilitate credit assignment and promote accurate perceptions in non-stationary environments. We summarize recent work that supports this idea and highlight open questions as well as alternative views of how arousal affects cognition.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.