Evidence map›Paper›PMID 39071879›Full record

ArticleVirusdisease2024

p38-MAPK is prerequisite for the synthesis of SARS-CoV-2 protein.

Priyasi Mittal, Nitin Khandelwal, Yogesh Chander, Assim Verma, Ram Kumar, Chayanika Putatunda, Sanjay Barua, Baldev Raj Gulati, Naveen Kumar

Abstract read
In one paragraph

Article in Virusdisease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Priyasi MittalNational Centre for Veterinary Type Cultures, ICAR-National Research Centre on Equines, Hisar, Haryana 125001 India.
Nitin KhandelwalNational Centre for Veterinary Type Cultures, ICAR-National Research Centre on Equines, Hisar, Haryana 125001 India.
Yogesh ChanderNational Centre for Veterinary Type Cultures, ICAR-National Research Centre on Equines, Hisar, Haryana 125001 India.
Assim VermaNational Centre for Veterinary Type Cultures, ICAR-National Research Centre on Equines, Hisar, Haryana 125001 India.
Ram KumarNational Centre for Veterinary Type Cultures, ICAR-National Research Centre on Equines, Hisar, Haryana 125001 India.
Chayanika PutatundaOm Sterling Global University (OSGU), Hisar, Haryana 125001 India.
Sanjay BaruaNational Centre for Veterinary Type Cultures, ICAR-National Research Centre on Equines, Hisar, Haryana 125001 India.
Baldev Raj GulatiNational Centre for Veterinary Type Cultures, ICAR-National Research Centre on Equines, Hisar, Haryana 125001 India.
Naveen KumarNational Centre for Veterinary Type Cultures, ICAR-National Research Centre on Equines, Hisar, Haryana 125001 India.ORCID 0000-0003-3974-9409

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The inhibition of p38 mitogen-activated protein kinase (p38-MAPK) by small molecule chemical inhibitors was previously shown to impair severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication, however, mechanisms underlying antiviral activity remains unexplored. In this study, reduced growth of SARS-CoV-2 in p38-

Indexed as

Host-directed antiviralsp38-MAPKProtein synthesisSARS-CoV-2SB203580

Identifiers

PMID39071879
PMCPMC11269555

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.