Evidence map›Paper›PMID 39071981›Full record

ArticleNeurotrauma reports2024

Bayesian Methods: A Means of Improving Statistical Power in Preclinical Neurotrauma?

Peyton M Mueller, Abel Torres-Espín, Cole Vonder Haar

Abstract read
In one paragraph

Article in Neurotrauma reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Peyton M MuellerDepartment of Neuroscience, Injury and Recovery Laboratory, Ohio State University, Columbus, Ohio, USA.
Abel Torres-EspínSchool of Public Health Sciences, University of Waterloo, Waterloo, Canada.
Cole Vonder HaarDepartment of Neuroscience, Injury and Recovery Laboratory, Ohio State University, Columbus, Ohio, USA.

Funding

Dopamine modulation for the treatment of chronic dysfunction due to traumatic brain injuryR01NS110905 · NINDS · WEST VIRGINIA UNIVERSITY · PI VONDER HAAR, COLE · 2019 to 2023
$1.7M
NINDS NIH HHS R01 NS110905
6 · The paper itself

Abstract

The field of neurotrauma is grappling with the effects of the recently identified replication crisis. As such, care must be taken to identify and perform the most appropriate statistical analyses. This will prevent misuse of research resources and ensure that conclusions are reasonable and within the scope of the data. We anticipate that Bayesian statistical methods will see increasing use in the coming years. Bayesian methods integrate prior beliefs (or prior data) into a statistical model to merge historical information and current experimental data. These methods may improve the ability to detect differences between experimental groups (i.e., statistical power) when used appropriately. However, researchers need to be aware of the strengths and limitations of such approaches if they are to implement or evaluate these analyses. Ultimately, an approach using Bayesian methodologies may have substantial benefits to statistical power, but caution needs to be taken when identifying and defining prior beliefs.

Indexed as

data analysishypothesis testingstatistics

Identifiers

PMID39071981
PMCPMC11271152

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.