Evidence map›Paper›PMID 39071983›Full record

ArticleNeurotrauma reports2024

The Influence of CYP2B6 Variants and Administration of Propofol on Patient Outcomes after Traumatic Brain Injury.

Katherine O'Meara, Ava M Puccio, Dianxu Ren, Sandra Deslouches, Ruchira Jha, David O Okonkwo, Yvette P Conley

Abstract read
In one paragraph

Article in Neurotrauma reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Katherine O'MearaUniversity of Pittsburgh School of Nursing, Pittsburgh, Pennsylvania, USA.
Ava M PuccioDepartment of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Dianxu RenUniversity of Pittsburgh School of Nursing, Pittsburgh, Pennsylvania, USA.
Sandra DeslouchesUniversity of Pittsburgh School of Nursing, Pittsburgh, Pennsylvania, USA.
Ruchira JhaDepartment of Neurology, Translational Neurosciences, Neurosurgery, Barrow Neurological Institute, Phoenix, Arizona, USA.ORCID https://orcid.org/0000-0002-3047-7649
David O OkonkwoDepartment of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Yvette P ConleyUniversity of Pittsburgh School of Nursing, Pittsburgh, Pennsylvania, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Management of severe traumatic brain injury (sTBI) typically involves the use of sedation, which inherently results in benefits and risks. The cytochrome P450 enzyme CYP2B6 is involved in the biotransformation of particular drug classes, including many intravenous sedatives. Variants of the

Indexed as

cytochrome P-450 CYP2B6sedativestraumatic brain injury

Identifiers

PMID39071983
PMCPMC11271148

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.