Evidence map›Paper›PMID 39074603›Full record

ReviewThe journal of allergy and clinical immunology. In practice2024

An Overview of Adherence-What It Is and Why It Is Important.

Ellen R Conroy, Tina M Banzon, Tregony Simoneau, Wanda Phipatanakul, Job F M van Boven, Désirée Larenas-Linnemann

Abstract readReview
In one paragraph

Review in The journal of allergy and clinical immunology. In practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Medication-related perceptions of children and adolescents with severe asthma and moderate-to-severe atopic dermatitis: a non-interventional exploratory study.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2025
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ellen R ConroyDivision of Immunology, Department of Medicine, Boston Children's Hospital, Boston, Mass; Harvard Medical School, Boston, Mass.
Tina M BanzonDivision of Immunology, Department of Medicine, Boston Children's Hospital, Boston, Mass; Harvard Medical School, Boston, Mass.
Tregony SimoneauHarvard Medical School, Boston, Mass; Division of Pulmonology, Department of Medicine, Boston Children's Hospital, Boston, Mass.
Wanda PhipatanakulDivision of Immunology, Department of Medicine, Boston Children's Hospital, Boston, Mass; Harvard Medical School, Boston, Mass.
Job F M van BovenDepartment of Clinical Pharmacy & Pharmacology, Groningen Research Institute for Asthma and COPD (GRIAC), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands; Medication Adherence Expertise Center Of the Northern Netherlands (MAECON), Groningen, The Netherlands.
Désirée Larenas-LinnemannCenter of Excellence in Asthma and Allergy, Medica Sur Clinical Foundation and Hospital, Mexico City, Mexico. Electronic address: marlar1@prodigy.net.mx.

Funding

Controlling and preventing Asthma progression and Severity in Kids (CASK)U01AI126614 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI PHIPATANAKUL, WANDA · 2016 to 2023
$21.0M
MOLECULAR BASIS OF ALLERGIC AND IMMUNOLOGIC DISEASET32AI007512 · NIAID · CHILDREN'S HOSPITAL BOSTON · PI Janet Chou, Peter A Nigrovic · 1996 to 2026
$13.1M
Effect of IL-4RαR576 variant on response to Dupilumab in children with AsthmaU01AI143514 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI CHATILA, TALAL AMINE, PHIPATANAKUL, WANDA · 2019 to 2023
$8.4M
Midcareer Investigator Award: Urban School Allergen Exposures and Childhood AsthmK24AI106822 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI PHIPATANAKUL, WANDA · 2013 to 2022
$1.9M
Evaluation of radon progeny and air pollution effects in asthmaK23ES035459 · NIEHS · BOSTON CHILDREN'S HOSPITAL · PI Tina Banzon · 2023 to 2026
$830k
NIAID NIH HHS K24 AI106822NIAID NIH HHS T32 AI007512NIAID NIH HHS U01 AI126614NIAID NIH HHS U01 AI143514NIEHS NIH HHS K23 ES035459
6 · The paper itself

Abstract

Asthma, allergic rhinitis, and food allergy are common allergic diseases, yet adherence to many management options remains poor, leading to worse health outcomes and financial implications for society and health systems. The underlying causes of nonadherence are numerous, ranging from patient-specific factors to broader socioeconomic and systems-based factors. In this review, we aim to discuss the definition of adherence, which can be divided into 3 components: initiation, implementation, and persistence, as well as to review various methods of measuring adherence. Subsequently, we will review the epidemiology of adherence to asthma and allergic rhinitis medications, allergen immunotherapy, and oral immunotherapy. Finally, we will discuss the multifaceted etiology of poor adherence and its subsequent impact on patients and society.

Indexed as

AsthmaDesensitization, ImmunologicMedication AdherenceRhinitis, AllergicFood HypersensitivityHumansAdherenceAllergic rhinitisAsthmaFood allergy

Identifiers

PMID39074603
PMCPMC11625628

What Socratic holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.