Evidence map›Paper›PMID 39075263›Full record

ArticleEye (London, England)2024

Anterior segment optical coherence tomography for the detection of silicone oil emulsification on the iris surface.

Mona Karsten, Matteo Morello, Imke Lau, Vasyl Druchkiv, Ines Valente Lopes, Simon Dulz, Christos Skevas, Martin Stephan Spitzer, Luca Mautone

Abstract read
In one paragraph

Article in Eye (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mona KarstenDepartment of Ophthalmology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. m.karsten@uke.de.ORCID http://orcid.org/0009-0006-0023-9793
Matteo MorelloCardiology School, University of Brescia, Brescia, Italy.
Imke LauDepartment of Ophthalmology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Vasyl DruchkivDepartment of Ophthalmology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Ines Valente LopesDepartment of Ophthalmology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Simon DulzDepartment of Ophthalmology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Christos SkevasDepartment of Ophthalmology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Martin Stephan SpitzerDepartment of Ophthalmology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Luca MautoneDepartment of Ophthalmology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo investigate the presence of silicone oil (SO)-emulsification on the anterior iris surface with anterior segment optical coherence tomography (AS-OCT).

methodsIn this single-center cross-sectional study, vitrectomized eyes with SO tamponade that underwent AS-OCT imaging and gonioscopy examination during the postoperative follow-up visits, were reviewed.

results45 eyes of 42 consecutive patients were included. In 35.6% of the eyes (n = 16) emulsified SO droplets were detected in the anterior chamber (AC) angle by gonioscopy and in 55.6% (n = 25) on the anterior iris surface by AS-OCT imaging. The presence of SO emulsifications in the AC-angle correlated with the presence of SO emulsifications on the anterior iris surface (OR = 13.4, 95% CI [2.179-82.130]; p = 0.005). The accuracy of the AS-OCT predicting the presence of SO in the AC-angle was 71.0% and the sensitivity was 87.5%. No significant association between SO droplets in the AC and other clinical parameters including endotamponade-duration or type of silicone oil were found. The presence of emulsified SO droplets on the anterior iris surface detected by AS-OCT was significantly correlated to postoperative IOP rise (p = 0.027).

conclusionAS-OCT is a suitable method for the detection of SO on the anterior iris surface. SO droplets on the iris surface correlate with elevated postoperative IOP and with the presence of SO in the AC detected by gonioscopy, therefore AS-OCT might be used as a screening method for the detection of SO migration into the AC. TRIAL REGISTRATION NUMBER: Institutional Review Board of the Hamburg Medical Chamber (Ethik-Kommission der Ärztekammer Hamburg): 2023-300372-WF.

Indexed as

EndotamponadeGonioscopySilicone OilsTomography, Optical CoherenceVitrectomyAdultAgedAnterior Eye SegmentCross-Sectional StudiesEmulsionsFemaleHumansIntraocular PressureIrisIris DiseasesMaleEmulsionsSilicone Oils

Identifiers

PMID39075263
PMCPMC11543845

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.