Evidence mapPaperPMID 39076567Full record

ArticleReviews in cardiovascular medicine2024

Sex-Related Differences in Cardiovascular Risk in Adolescents with Overweight or Obesity.

Procolo Di Bonito, Anna Di Sessa, Maria Rosaria Licenziati, Domenico Corica, Malgorzata Wasniewska, Emanuele Miraglia Del Giudice, Anita Morandi, Claudio Maffeis, Maria Felicia Faienza, Enza Mozzillo and 6 more

Abstract read
In one paragraph

Article in Reviews in cardiovascular medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Procolo Di BonitoDepartment of Internal Medicine, "S. Maria delle Grazie" Hospital, 80078 Pozzuoli, Italy.
Anna Di SessaDepartment of Woman, Child and of General and Specialized Surgery, Università degli Studi della Campania "Luigi Vanvitelli", 80138 Napoli, Italy.
Maria Rosaria LicenziatiNeuro-Endocrine Diseases and Obesity Unit, Department of Neurosciences, Santobono-Pausilipon Children's Hospital, 80129 Naples, Italy.
Domenico CoricaDepartment of Human Pathology in Adulthood and Childhood, University of Messina, 98122 Messina, Italy.
Malgorzata WasniewskaDepartment of Human Pathology in Adulthood and Childhood, University of Messina, 98122 Messina, Italy.
Emanuele Miraglia Del GiudiceDepartment of Woman, Child and of General and Specialized Surgery, Università degli Studi della Campania "Luigi Vanvitelli", 80138 Napoli, Italy.
Anita MorandiDepartment of Surgery, Dentistry, Pediatrics and Gynecology, Section of Pediatric Diabetes and Metabolism, University and Azienda Ospedaliera Universitaria Integrata of Verona, 37126 Verona, Italy.
Claudio MaffeisDepartment of Surgery, Dentistry, Pediatrics and Gynecology, Section of Pediatric Diabetes and Metabolism, University and Azienda Ospedaliera Universitaria Integrata of Verona, 37126 Verona, Italy.
Maria Felicia FaienzaPediatric Unit, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari "Aldo Moro", 70124 Bari, Italy.
Enza MozzilloDepartment of Translational Medical Science, Section of Pediatrics, Regional Center of Pediatric Diabetes, University of Naples "Federico II", 80131 Napoli, Italy.
Valeria CalcaterraPediatric Department, "V. Buzzi" Children's Hospital, 20154 Milano, Italy.
Francesca FrancoPediatric Department, Azienda Sanitaria Universitaria del Friuli Centrale, Hospital of Udine, 33100 Udine, Italy.
Giulio MaltoniPediatric Unit, IRCCS Azienda Ospedaliero-universitaria di Bologna, 40138 Bologna, Italy.
Nicola MoioDepartment of Cardiology, "S. Maria delle Grazie" Hospital, 80078 Pozzuoli, Italy.
Arcangelo IannuzziDepartment of Medicine and Medical Specialties, A. Cardarelli Hospital, 80131 Naples, Italy.
Giuliana ValerioDepartment of Medical, Movement and Wellbeing Sciences, University of Napoli "Parthenope", 80133 Napoli, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pediatric obesity is closely associated with cardiometabolic comorbidities, but the role of sex in this relationship is less investigated. We aimed to evaluate sex-related differences on cardiometabolic risk factors and preclinical signs of target organ damage in adolescents with overweight/obesity (OW/OB). Methods: The main cross-sectional study included 988 adolescents (510 boys and 478 girls) with OW/OB aged 10-18 years. In all youths clinical and biochemical variables were evaluated and an abdominal echography was performed. Echocardiographic data for the assessment of left ventricular mass (LVM) and relative wall thickness (RWT) were available in an independent sample of 142 youths (67 boys and 75 girls), while echographic data of carotid intima media thickness (cIMT) were available in 107 youths (59 boys and 48 girls). Results: The three samples did not differ for age, body mass index, and sex distribution. In the main sample, boys showed higher waist-to-height ratio (WHtR) values ( Conclusions: Adolescent boys with OW/OB showed higher risk of abdominal adiposity, FLD, and increased cardiac and vascular impairment than girls, whereas the latter had a higher risk of MReGFR. Risk stratification by sex for cardiometabolic risk factors or preclinical signs of target organ damage should be considered in youths with OW/OB.

Indexed as

adolescentscardiometabolic riskcarotid intima media thicknessestimated glomerular filtration ratefatty liver diseaseleft ventricular masssexvisceral adiposity

Identifiers

PMID39076567
PMCPMC11264036

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.