Evidence mapPaperPMID 39076977Full record

ReviewFrontiers in immunology2024

Ferroptosis and endoplasmic reticulum stress in rheumatoid arthritis.

Qin Ao, Huan Hu, Ying Huang

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Observational
  2. Review
  3. The Application Prospects and Future Outlook ofDrug design, development and therapy · 2026
    Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Iron metabolism in rheumatic diseases.Journal of translational autoimmunity · 2025
    Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. CUR-PDT induces ferroptosis of RA-FLS via the Nrf2/xCT/GPX4 pathway to inhibit proliferation in rheumatoid arthritis.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
    Article
  15. SIRT6 inhibits endoplasmic reticulum stress-mediated ferroptosis by activating Nrf2/HO-1 signaling to alleviate osteoarthritis.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
    Article
  16. Review
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Qin AoGuizhou Universisity of Traditional Chinese Medicine, Guiyang, China.
Huan HuCenter for General Practice Medicine, Department of Rheumatology and Immunology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), Hangzhou, China.
Ying HuangGuizhou Universisity of Traditional Chinese Medicine, Guiyang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ferroptosis is an iron-dependent mode of cell death distinct from apoptosis and necrosis. Its mechanisms mainly involve disordered iron metabolism, lipid peroxide deposition, and an imbalance of the antioxidant system. The endoplasmic reticulum is an organelle responsible for protein folding, lipid metabolism, and Ca

Indexed as

Arthritis, RheumatoidEndoplasmic Reticulum StressFerroptosisAnimalsHumansIronOxidative StressSignal TransductionUnfolded Protein ResponseIronendoplasmic reticulum stressferroptosislipid peroxidationreactive oxygen speciesrheumatoid arthritisunfolded protein response

Identifiers

PMID39076977
PMCPMC11284608

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.