SynthesisReviews in cardiovascular medicine2023
Timing of Complete Revascularization in Patients with STEMI and Multivessel Disease: A Systematic Review and Meta-Analysis.
Synthesis in Reviews in cardiovascular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Comparative Outcomes of Fractional Flow Reserve and Intravascular Ultrasound Guidance for Percutaneous Coronary Intervention in Intermediate Lesions: A Systematic Review and Meta-Analysis.Cardiovascular therapeutics · 2026Pooled it
- Meta-analysis of immediate complete vs staged complete revascularization in patients with acute coronary syndrome and multivessel disease.Cardiovascular revascularization medicine : including molecular interventions · 2024Pooled it
- Trial
- Sex-Specific Prognostic Value of Left Atrioventricular Coupling Index in Acute Coronary Syndrome: Insights From Artificial Intelligence-Enhanced 3-Dimensional Echocardiography.Journal of the American Heart Association · 2026Article
- Non-invasive estimation of coronary resistance and compliance: Prospective diagnostic study vs. angiography.American heart journal plus : cardiology research and practice · 2026Article
- Impact of Coronary Artery Disease Extent on GRACE Risk Score Prognostic Performance After ST-Segment-Elevation Myocardial Infarction.Journal of the American Heart Association · 2026Article
- Reliability of Immersive Virtual Reality for Pre-Procedural Planning for TAVI: A CT-Based Validation.Journal of cardiovascular development and disease · 2025Article
- Use of Calcium Modification in Percutaneous Coronary Intervention: A Comprehensive Review.Journal of clinical medicine · 2025Review
- Comparative Impact of Coronary Imaging Strategies in CTO-PCI: A Retrospective Single-Center Analysis.Journal of clinical medicine · 2025Article
- When Functional Assessment Meets Intravascular Imaging in Patients with Coronary Artery Disease.Journal of cardiovascular development and disease · 2025Review
- Predictive value of clinical syntax score for clinical outcomes on patients with acute coronary syndrome undergoing rotational atherectomy.BMC cardiovascular disorders · 2025Article
- Sex differences based on the timing of invasive management among patients with non-ST-elevation acute coronary syndrome: an individual patient data meta-analysis.European heart journal open · 2025Article
- Practice patterns and percutaneous coronary intervention outcomes: a comparison between Sweden and the US.European heart journal open · 2025Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: About half of patients with ST-segment Elevation Myocardial Infarction (STEMI) have multivessel coronary artery disease (MVD). Our aim was to provide a quantitative comparison of single-stage complete revascularization during the index revascularization versus deferred staged complete revascularization in STEMI patients with MVD. Methods: All studies evaluating patients with STEMI and MVD were included. The primary endpoint was a composite of all-cause death, myocardial infarction and repeat revascularization. Secondary endpoints were cardiovascular death, acute kidney injury and trial defined major bleeding. Results: Eight studies and 2256 patients with STEMI and MVD were included. No difference was evident in the rate of the primary composite endpoint among the study group (Risk Ratio 0.95; 95% CI 0.71-1.27, Conclusions: Our analysis documented similar clinical outcomes with either single-stage immediate complete revascularization and delayed staged complete revascularization. Secondary analyses suggest that an increase in cardiovascular death might be expected with single-stage percutaneous coronary intervention (PCI). While new randomized trials on the topic are ongoing, revascularization can be personalized and guided by the acute clinical setting, patients'-related factors and workflow logistics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.