Evidence map›Paper›PMID 39078539›Full record

ArticleCurrent environmental health reports2024

Exposure to Endocrine Disruptors in Early life and Neuroimaging Findings in Childhood and Adolescence: a Scoping Review.

Kim N Cajachagua-Torres, Hugo G Quezada-Pinedo, Tong Wu, Leonardo Trasande, Akhgar Ghassabian

Abstract readScoping Review
In one paragraph

Article in Current environmental health reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. EndoCompass Project: Environmental Endocrinology.Hormone research in paediatrics · 2025
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kim N Cajachagua-TorresDepartment of Pediatrics, NYU Grossman School of Medicine, 555 First Avenue, New York, NY, 10016, USA. kimnail.cajachaguatorres@nyulangone.org.
Hugo G Quezada-PinedoDepartment of Pediatrics, Erasmus MC, Erasmus University Rotterdam, Rotterdam, The Netherlands.
Tong WuDepartment of Radiology and Nuclear Medicine, Erasmus MC, Erasmus University Rotterdam, Rotterdam, The Netherlands.
Leonardo TrasandeDepartment of Pediatrics, NYU Grossman School of Medicine, 555 First Avenue, New York, NY, 10016, USA.
Akhgar GhassabianDepartment of Pediatrics, NYU Grossman School of Medicine, 555 First Avenue, New York, NY, 10016, USA.

Funding

The NYU Children’s Health & Environment Study: an ECHO CohortUG3OD023305 · OD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI TRASANDE, LEONARDO · 2016 to 2024
$26.5M
8/24 The Healthy Brain and Child Development National ConsortiumU01DA055338 · NIDA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Obianuju Berry, Lauren Christine Shuffrey · 2021 to 2026
$9.4M
Brain Influences of Phthalates and Bisphenols in AdolescentsR01ES032826 · NIEHS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Akhgar Ghassabian · 2021 to 2026
$2.8M
NIDA NIH HHS U01 DA055338NIEHS NIH HHS R01 ES032826NIH HHS UG3 OD023305
6 · The paper itself

Abstract

PURPOSE OF REVIEW: Evidence suggests neurotoxicity of endocrine disrupting chemicals (EDCs) during sensitive periods of development. We present an overview of pediatric population neuroimaging studies that examined brain influences of EDC exposure during prenatal period and childhood. RECENT

findingsWe found 46 studies that used magnetic resonance imaging (MRI) to examine brain influences of EDCs. These studies showed associations of prenatal exposure to phthalates, organophosphate pesticides (OPs), polyaromatic hydrocarbons and persistent organic pollutants with global and regional brain structural alterations. Few studies suggested alteration in functional MRI associated with prenatal OP exposure. However, studies on other groups of EDCs, such as bisphenols, and those that examined childhood exposure were less conclusive. These findings underscore the potential profound and lasting effects of prenatal EDC exposure on brain development, emphasizing the need for better regulation and strategies to reduce exposure and mitigate impacts. More studies are needed to examine the influence of postnatal exposure to EDC on brain imaging.

Indexed as

BrainEndocrine DisruptorsNeuroimagingPrenatal Exposure Delayed EffectsAdolescentChildChild, PreschoolEnvironmental ExposureEnvironmental PollutantsFemaleHumansMagnetic Resonance ImagingPersistent Organic PollutantsPesticidesPhthalic AcidsPregnancyEndocrine DisruptorsEnvironmental PollutantsPersistent Organic PollutantsPesticidesPhthalic AcidsBrainEndocrine disruptorsEpidemiological studiesNeuroimaging

Identifiers

PMID39078539
PMCPMC11324673

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.