Evidence map›Paper›PMID 39080451›Full record

ArticleScientific reports2024

Childhood obesity is associated with a high degree of metabolic disturbance in children from Brazilian semi-arid region.

Isabella B B Ferreira, Alexvon N Gomes, Isadora B C Almeida, Mariana D Fernandes, Ludmilla F Coutinho, Renata Lago, Camilla A Menezes, Nelzair A Vianna, Ricardo R Oliveira, Eduardo R Fukutani and 3 more

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Isabella B B FerreiraPrograma de Pós-Graduação em Medicina e Saúde Humana, Escola Bahiana de Medicina e Saúde Pública (EBMSP), Salvador, Bahia, Brazil.
Alexvon N GomesPrograma de Pós-Graduação em Medicina e Saúde Humana, Escola Bahiana de Medicina e Saúde Pública (EBMSP), Salvador, Bahia, Brazil.
Isadora B C AlmeidaPrograma de Pós-Graduação em Medicina e Saúde Humana, Escola Bahiana de Medicina e Saúde Pública (EBMSP), Salvador, Bahia, Brazil.
Mariana D FernandesPrograma de Pós-Graduação em Medicina e Saúde Humana, Escola Bahiana de Medicina e Saúde Pública (EBMSP), Salvador, Bahia, Brazil.
Ludmilla F CoutinhoCurso de Medicina, Universidade Salvador (UNIFACS), Salvador, Bahia, Brazil.
Renata LagoPrograma de Pós-Graduação em Medicina e Saúde Humana, Escola Bahiana de Medicina e Saúde Pública (EBMSP), Salvador, Bahia, Brazil.
Camilla A MenezesInstituto Gonçalo Moniz (IGM), Fundação Oswaldo Cruz (Fiocruz), Rua Waldemar Falcão, 121, Candeal, Salvador, Bahia, 40296-710, Brazil.
Nelzair A ViannaInstituto Gonçalo Moniz (IGM), Fundação Oswaldo Cruz (Fiocruz), Rua Waldemar Falcão, 121, Candeal, Salvador, Bahia, 40296-710, Brazil.
Ricardo R OliveiraInstituto Gonçalo Moniz (IGM), Fundação Oswaldo Cruz (Fiocruz), Rua Waldemar Falcão, 121, Candeal, Salvador, Bahia, 40296-710, Brazil.
Eduardo R FukutaniInstituto Gonçalo Moniz (IGM), Fundação Oswaldo Cruz (Fiocruz), Rua Waldemar Falcão, 121, Candeal, Salvador, Bahia, 40296-710, Brazil.
Rodrigo C MenezesInstituto de Pesquisa Clínica e Translacional, Faculdade Zarns, Clariens Educação, Salvador, Bahia, Brazil.
Ana Marice LadeiaPrograma de Pós-Graduação em Medicina e Saúde Humana, Escola Bahiana de Medicina e Saúde Pública (EBMSP), Salvador, Bahia, Brazil.
Bruno B AndradeInstituto de Pesquisa Clínica e Translacional, Faculdade Zarns, Clariens Educação, Salvador, Bahia, Brazil. bruno.andrade@fiocruz.br.

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico Senior fellowshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior Finance code 001Ministério Público do Estado da Bahia Sustainable School Program
6 · The paper itself

Abstract

Projected to impact 310 million children by the next decade, childhood obesity is linked to serious health issues like metabolic disturbance and cardiovascular diseases. This study introduces a novel approach for the integrated assessment of inflammatory, glycemic and lipid disorders in obese children in resources-limited settings and also identifies key factors contributing to these changes. Conducting a cross-sectional analysis of 231 children aged 5-12 years from public schools in Brazil's semi-arid region, the research involved collecting medical history, anthropometric measurements, and blood samples to analyze glycemic and lipid profiles, along with C-reactive protein levels. We used an adapted the Molecular Degree of Perturbation model to analyze deviations in metabolic markers from a healthy control group. Statistical analyses included Mann-Whitney and Fisher exact tests, backward logistic regression, and hierarchical cluster analysis. The study identified a direct and independent association between elevated Metabolic Disturbance Degree and both overweight and obesity in children, with significant differences in CRP, Triglycerides, and HDL levels noted between obese and healthy-weight groups. The findings highlight the critical need for early detection and comprehensive understanding of obesity-related changes to mitigate the severe health risks associated with childhood obesity.

Indexed as

Pediatric ObesityBiomarkersBrazilChildChild, PreschoolC-Reactive ProteinCross-Sectional StudiesFemaleHumansMaleMetabolic DiseasesTriglyceridesBiomarkersC-Reactive ProteinTriglycerides

Identifiers

PMID39080451
PMCPMC11289272

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.