Evidence map›Paper›PMID 39083167›Full record

ArticleChild psychiatry and human development2026

Validation of the ND-PAE Diagnosis in Children with Heavy Prenatal Alcohol Exposure.

Christina R Veziris, Matthew T Hyland, Julie A Kable, Jeffrey R Wozniak, Claire D Coles, Philip A May, Wendy O Kalberg, Elizabeth R Sowell, Kenneth L Jones, Edward P Riley and 1 more

Abstract readValidation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Child psychiatry and human development, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Christina R VezirisCenter for Behavioral Teratology and Department of Psychology, San Diego State University, 6330 Alvarado Court, Suite 100, San Diego, CA, 92120, USA.
Matthew T HylandCenter for Behavioral Teratology and Department of Psychology, San Diego State University, 6330 Alvarado Court, Suite 100, San Diego, CA, 92120, USA.
Julie A KableDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, USA.
Jeffrey R WozniakDepartment of Psychiatry and Behavioral Sciences, University of Minnesota, Minneapolis, USA.
Claire D ColesDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, USA.
Philip A MayNutrition Research Institute, University of North Carolina, Chapel Hill, USA.
Wendy O KalbergCenter On Alcoholism, Substance Abuse, and Addiction, University of New Mexico, Albuquerque, USA.
Elizabeth R SowellDepartment of Pediatrics, Neurology, and Psychology, Keck School of Medicine of USC, Los Angeles, USA.
Kenneth L JonesDepartment of Pediatrics, University of California San Diego School of Medicine, San Diego, USA.
Edward P RileyCenter for Behavioral Teratology and Department of Psychology, San Diego State University, 6330 Alvarado Court, Suite 100, San Diego, CA, 92120, USA.
Sarah N MattsonCenter for Behavioral Teratology and Department of Psychology, San Diego State University, 6330 Alvarado Court, Suite 100, San Diego, CA, 92120, USA. sarah.mattson@sdsu.edu.

Funding

Cross-Cultural Assessment of FASDU24AA014811 · NIAAA · SAN DIEGO STATE UNIVERSITY · PI EDWARD P RILEY · 2003 to 2026
$13.1M
FASD in San Diego and Moscow (U01 Research Project)U01AA014834 · NIAAA · SAN DIEGO STATE UNIVERSITY · PI SARAH N MATTSON WELLER · 2003 to 2026
$12.4M
Alcohol Research in the Science/Practitioner ModelT32AA013525 · NIAAA · SAN DIEGO STATE UNIVERSITY · PI EDWARD P RILEY, ANDREA SPADONI TOWNSEND · 2002 to 2026
$8.4M
FASD Diagnostic Telemedicine ResourceU24AA014815 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Lauren Gist, SARAH N MATTSON WELLER · 2003 to 2026
$5.6M
tDCS and cognitive training as a neurodevelopmental intervention in FASDU01AA030164 · NIAAA · UNIVERSITY OF MINNESOTA · PI Jeffrey Robert Wozniak · 2022 to 2026
$2.2M
Multi-modal connectivity methods for the validation of Fetal Alcohol Spectrum Disorder diagnostic criteriaU01AA026102 · NIAAA · UNIVERSITY OF MINNESOTA · PI WOZNIAK, JEFFREY ROBERT · 2017 to 2021
$1.7M
NIAAA NIH HHS T32 AA013525NIAAA NIH HHS U01 AA014834NIAAA NIH HHS U01 AA026102NIAAA NIH HHS U01 AA030164NIAAA NIH HHS U24 AA014811NIAAA NIH HHS U24 AA014815
6 · The paper itself

Abstract

This study evaluated criteria for neurobehavioral disorder associated with prenatal alcohol exposure (ND-PAE). Kable et al. (Child Psychiatry Hum Dev 55:426, 2022) assessed the validity of this diagnosis in a sample with low exposure to alcohol. The current study expanded this assessment to a sample with a wider age range and heavier alcohol exposure. Data were collected from participants (5-17 years) with prenatal alcohol exposure (PAE) and typically developing controls at six Collaborative Initiative on Fetal Alcohol Spectrum Disorders sites using neuropsychological assessment and caregiver reports. Impairment was tested at 1SD, 1.5SD, and 2SD below the normative average and a modification of the adaptive functioning requirement was tested. Testing impairment at 1SD resulted in the highest endorsement rates in both groups. Our findings replicated the study by Kable et al. and show that current criteria captured a high rate of those with PAE and that requiring fewer adaptive functioning criteria resulted in higher sensitivity to PAE.

Indexed as

Fetal Alcohol Spectrum DisordersPrenatal Exposure Delayed EffectsAdolescentChildChild, PreschoolFemaleHumansMaleNeuropsychological TestsPregnancyReproducibility of ResultsDiagnosisFetal alcohol spectrum disorders (FASD)Neurobehavioral disorder associated with prenatal alcohol exposure (ND-PAE)Prenatal alcohol exposureValidity

Identifiers

PMID39083167
PMCPMC11831386

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.