Evidence map›Paper›PMID 39083208›Full record

ArticleJournal of veterinary science2024

Epidemiological, and molecular investigation of

Eman Farag Ammar, Yamen Mohammed Hegazy, Magdy Al-Gaabary, Samah M Mosad, Mohamed Salem, Mohamed Marzok, Fadhel Housawi, Mohamed Al-Ali, Abdulrahman Alhaider, Amin Tahoun

Abstract read
In one paragraph

Article in Journal of veterinary science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Eman Farag AmmarDepartment of Animal Medicine, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafrelsheikh 33511, Egypt.ORCID https://orcid.org/0009-0001-1037-9566
Yamen Mohammed HegazyDepartment of Animal Medicine, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafrelsheikh 33511, Egypt.ORCID https://orcid.org/0000-0002-7355-8238
Magdy Al-GaabaryDepartment of Animal Medicine, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafrelsheikh 33511, Egypt.ORCID https://orcid.org/0000-0002-5048-8943
Samah M MosadDepartment of Virology, Faculty of Veterinary Medicine, Mansoura University, Mansoura 35516, Egypt.ORCID https://orcid.org/0000-0003-4533-4904
Mohamed SalemDepartment of Clinical Sciences, College of Veterinary Medicine, King Faisal University, Al-Ahsa 31982, Saudi Arabia.ORCID https://orcid.org/0009-0000-1995-4814
Mohamed MarzokDepartment of Clinical Sciences, College of Veterinary Medicine, King Faisal University, Al-Ahsa 31982, Saudi Arabia.ORCID https://orcid.org/0000-0002-7961-1247
Fadhel HousawiDepartment of Clinical Sciences, College of Veterinary Medicine, King Faisal University, Al-Ahsa 31982, Saudi Arabia.ORCID https://orcid.org/0000-0003-3423-7594
Mohamed Al-AliDepartment of Clinical Sciences, College of Veterinary Medicine, King Faisal University, Al-Ahsa 31982, Saudi Arabia.ORCID https://orcid.org/0009-0009-9741-048X
Abdulrahman AlhaiderDepartment of Clinical Sciences, College of Veterinary Medicine, King Faisal University, Al-Ahsa 31982, Saudi Arabia.ORCID https://orcid.org/0000-0003-3863-997X
Amin TahounDepartment of Animal Medicine, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafrelsheikh 33511, Egypt.ORCID https://orcid.org/0000-0002-9239-622X

Funding

Deanship of Scientific Research, King Faisal University A359
6 · The paper itself

Abstract

importanceCanine parvovirus enteritis (CPE) is a contagious viral disease of dogs caused by the canine parvovirus-2 (CPV-2) associated with high morbidity and mortality rates. CPV-2 has a high global evolutionary rate. Molecular characterization of CPV-2 and understanding its epidemiology are essential for controlling CPV-2 infections.

objectiveThis study examined the risk factors and survival outcomes of dogs infected with CPV-2. Molecular characterization of CPV-2 genotypes circulating in Egypt was performed to determine the evolution of CPV-2 nationally and globally.

methodsAn age-matched case-control study was conducted on 47 control and 47 CPV-infected dogs. Conditional logistic regression analysis examined the association between the potential risk factors and CPE in dogs. Survival analysis was performed to determine the survival pattern of the infected dogs. Thirteen fecal samples from infected dogs were collected to confirm the CPV genotype by CPV-2 VP2 gene sequencing, assembly of nucleotide sequences, and phylogenic analysis.

resultsUnvaccinated and roamer dogs had eight and 2.3 times higher risks of CPV infection than vaccinated dogs and non-roamer dogs, respectively. The risk of death from CPE was high among dogs without routine visits to veterinary clinics and among non-roamer dogs. Molecular characterization of CPV-2 confirmed its genotype identity and relationship with the CPV-2 c and b clade types. CONCLUSIONS AND RELEVANCE: This study highlights the potential factors for CPE control, especially vaccination and preventing dogs from roaming freely outside houses. Isolated CPV genotypes are closely related to southern Asian genotypes, suggesting a substantial opportunity for global transmission.

Indexed as

Dog DiseasesParvoviridae InfectionsParvovirus, CanineAnimalsCase-Control StudiesDogsEgyptFecesFemaleGenotypeMalePhylogenyRisk FactorsCanine parvoviruscase-control studyphylogenetic biogeographyrisk factorssequence analysis

Identifiers

PMID39083208
PMCPMC11291436

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.