Evidence map›Paper›PMID 39085664›Full record

Trial reportSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2024

Auriculotherapy and acupuncture treatments for chemotherapy-induced nausea and vomiting: a multicenter clinical trial.

Mireille Michel-Cherqui, Sabrina Ma, Joy Bacrie, Sophie Huguet, Nicolas Lemaire, Morgan Le Guen, Marc Fischler

Registry-linked trialAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02767791 (Auriculotherapy and Acupuncture's Treatment for Chemotherapy-induced Nausea and Vomiting), which is not on this map. Cited by 5 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02767791 nacompletednot on this map

Auriculotherapy and Acupuncture's Treatment for Chemotherapy-induced Nausea and Vomiting (CINV)

TypeinterventionalSponsorHopital FochRan2016 to 2021Enrolled116ConditionsNausea, VomitingArmsAcupuncture, Auriculotherapy
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Efficacy of acupuncture in managing radiotherapy/chemotherapy-induced oral mucositis: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mireille Michel-CherquiDepartment of Anesthesiology and of Pain Management, Hôpital Foch, 40 Rue Worth, 92150, Suresnes, France.
Sabrina MaDepartment of Anesthesiology and of Pain Management, Hôpital Foch, 40 Rue Worth, 92150, Suresnes, France.
Joy BacrieDepartment of Medical Oncology, Curie Institute - Hospital Rene Huguenin, 92210, Saint-Cloud, France.
Sophie HuguetSupportive Care Department, Hôpital Emmanuel Rain, 95500, Gonesse, France.
Nicolas LemaireAxonal Biostatem, 92000, Nanterre, France.
Morgan Le GuenDepartment of Anesthesiology and of Pain Management, Hôpital Foch, 40 Rue Worth, 92150, Suresnes, France.
Marc FischlerDepartment of Anesthesiology and of Pain Management, Hôpital Foch, 40 Rue Worth, 92150, Suresnes, France. m.fischler@hopital-foch.com.ORCID http://orcid.org/0000-0003-0729-5430

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeNausea and vomiting complicating chemotherapy (CINV) remain side effects despite preventive and curative treatments. We hypothesize that acupuncture (ACU), auriculotherapy (AUR), and their combination (ACU-AUR), could decrease, compared to usual treatment (UT), the intensity of acute nausea in patients already treated according to the antiemetic guidelines and presenting nausea with or without vomiting in the earlier cycle.

methodsIn this multicenter study, patients were treated just before chemotherapy according to randomization. ACU consisted of implanting bilaterally on each forearm, one semi-permanent needle at point P6. AUR consisted of implanting bilaterally on each pavilion of the ear, one semi-permanent needle at point O. All patients received systematic preventive drug treatment according to antiemetic guidelines. Main outcome was intensity of nausea at 24 h after chemotherapy using a numeric scale ranging from 0 (no nausea) to 10 (maximum symptoms).

resultsOne hundred and fifteen patients were included. Baseline characteristics were similar between groups at inclusion. Intensity of nausea at 24 h after chemotherapy, was statistically different between the groups (covariance intergroup analysis, p = 0.005) and was significantly lower for the all-treatment groups vs UT group (p = 0.007 for AUR, p = 0.008 for ACU, and p = 0.0009 for AUR-ACU). AUR-ACU also decreased intensity of delayed nausea when compared to UT (p = 0.023). AUR, ACU and AUR-ACU had no effect on acute and delayed vomiting episodes. No serious adverse event due to the studied treatments was reported in our study.

conclusionAUR or ACU reduce intensity of acute and delayed nausea in patients treated by optimal antiemetic treatment. TRIAL REGISTRATION NUMBER: CLINICALTRIALS: gov identifier NCT02767791, registered on May 10, 2016.

Indexed as

Acupuncture TherapyAntineoplastic AgentsAuriculotherapyNauseaVomitingAdultAgedAntiemeticsFemaleHumansMaleMiddle AgedNeoplasmsAntiemeticsAntineoplastic AgentsAcupunctureAuriculotherapyCancerChemotherapyNauseaVomiting

Identifiers

PMID39085664

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.