Evidence mapPaperPMID 39086199Full record

ArticleEnvironmental science & technology2024

Prenatal and Early Life Exposure to Ambient Air Pollutants Is Associated with the Fecal Metabolome in the First Two Years of Life.

Elizabeth A Holzhausen, Bridget N Chalifour, Youran Tan, Nathan Young, Fred Lurmann, Dean P Jones, Jeremy A Sarnat, Howard H Chang, Michael I Goran, Donghai Liang and 1 more

Abstract read
In one paragraph

Article in Environmental science & technology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Prenatal Nitrogen Oxide (NOEnvironmental science & technology · 2025
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Elizabeth A HolzhausenDepartment of Integrative Physiology, University of Colorado Boulder, Boulder, Colorado 80309, United States.ORCID 0000-0002-1773-0099
Bridget N ChalifourDepartment of Integrative Physiology, University of Colorado Boulder, Boulder, Colorado 80309, United States.
Youran TanRollins School of Public Health, Emory University, Atlanta, Georgia 30322, United States.
Nathan YoungDepartment of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, United States.
Fred LurmannSonoma Technology Inc., Petaluma, California 94954, United States.
Dean P JonesRollins School of Public Health, Emory University, Atlanta, Georgia 30322, United States.
Jeremy A SarnatRollins School of Public Health, Emory University, Atlanta, Georgia 30322, United States.
Howard H ChangRollins School of Public Health, Emory University, Atlanta, Georgia 30322, United States.ORCID 0000-0002-6316-1640
Michael I GoranChildren's Hospital Los Angeles, Los Angeles, California 90027, United States.
Donghai LiangRollins School of Public Health, Emory University, Atlanta, Georgia 30322, United States.ORCID 0000-0001-7311-2298
Tanya L AldereteDepartment of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, United States.

Funding

PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Paul S. Maclean · 1995 to 2026
$32.6M
Southern California Center for Chronic Health Disparities in Latino Children and Families.P50MD017344 · NIMHD · CHILDREN'S HOSPITAL OF LOS ANGELES · PI COHEN, DEBORAH A · 2021 to 2025
$27.8M
Impact of Sugars and Human Milk Oligosaccharides on Infant Microbiome and ObesityR01DK110793 · NIDDK · UNIVERSITY OF SOUTHERN CALIFORNIA · PI GORAN, MICHAEL ISAAC, PETERSON, BRADLEY S · 2017 to 2024
$6.0M
Perfluoroalkyl Substances and the Gut Microbiome and Fecal Metabolome: Implications for Obesity Risk in Hispanic ChildrenR01ES035035 · NIEHS · UNIVERSITY OF COLORADO · PI Tanya Lynn Alderete · 2023 to 2026
$2.6M
Pre- and Postnatal Exposure to Air Pollutants and the Gut Microbiome: Implications for Brain Development in Early and Mid-ChildhoodR01ES035056 · NIEHS · UNIVERSITY OF COLORADO · PI Tanya Lynn Alderete, BRADLEY S PETERSON · 2024 to 2026
$2.1M
Transdisciplinary Training in Sleep and Circadian RhythmsT32HL149646 · NHLBI · UNIVERSITY OF COLORADO · PI Kenneth P Wright · 2020 to 2026
$1.6M
NHLBI NIH HHS T32 HL149646NIDDK NIH HHS P30 DK048520NIDDK NIH HHS R01 DK110793NIEHS NIH HHS R01 ES035035NIEHS NIH HHS R01 ES035056NIMHD NIH HHS P50 MD017344
6 · The paper itself

Abstract

Prenatal and early life air pollution exposure has been linked with several adverse health outcomes. However, the mechanisms underlying these relationships are not yet fully understood. Therefore, this study utilizes fecal metabolomics to determine if pre- and postnatal exposure to ambient air pollutants (i.e., PM

Indexed as

Air PollutantsFecesMetabolomeAir PollutionChild, PreschoolEnvironmental ExposureFemaleHumansInfantMalePregnancyPrenatal Exposure Delayed EffectsAir Pollutantsearly lifefecal metabolomicsNO2PM10PM2.5

Identifiers

PMID39086199
PMCPMC11325649

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.