Evidence map›Paper›PMID 39086661›Full record

ArticleFrontiers in cell and developmental biology2024

Ribosome heterogeneity in development and disease.

Yuen Gao, Hongbing Wang

Abstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. RiboScreenBiomedicines · 2026
    Review
  2. Review
  3. Review
  4. The ribosomal landscape in influenza A virus infection: from molecular mechanisms to clinical relevance.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  5. Review
  6. How Early-Life Programming During Embryogenesis Imprints Cellular Memory.International journal of molecular sciences · 2025
    Review
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Yuen GaoDepartment of Physiology, Michigan State University, East Lansing, MI, United States.
Hongbing WangDepartment of Physiology, Michigan State University, East Lansing, MI, United States.

Funding

Nonconventional role of ADCY in Gq-mediated neuronal signaling and neuroplasticityR01MH119149 · NIMH · MICHIGAN STATE UNIVERSITY · PI WANG, HONGBING · 2019 to 2023
$2.3M
Mechanism underlying cognitive and synaptic flexibilityR01MH124992 · NIMH · MICHIGAN STATE UNIVERSITY · PI WANG, HONGBING · 2021 to 2024
$2.0M
NIMH NIH HHS R01 MH119149NIMH NIH HHS R01 MH124992
6 · The paper itself

Abstract

Traditionally viewed as a fixed and homogeneous machinery for protein synthesis, the ribosome is increasingly recognized for its heterogeneity, as indicated by emerging studies highlighting the functional relevance of specialized ribosomes. However, whether ribosome heterogeneity is merely an outcome limited to specific conditions or a pervasive cellular phenomenon remains unclear, and existing evidence on the extensive existence of ribosome heterogeneity is scant. Here, we leveraged existing proteomic data and employed ribosome ratio-omics (Ribosome

Indexed as

bioinformaticscancerdevelopmentmacrophageribosome heterogeneitystoichiometry

Identifiers

PMID39086661
PMCPMC11288964

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.