Evidence map›Paper›PMID 39086833›Full record

ArticleRoyal Society open science2024

Recovery from social isolation requires dopamine in males, but not the autism-related gene

Ryley T Yost, Andrew M Scott, Judy M Kurbaj, Brendan Walshe-Roussel, Reuven Dukas, Anne F Simon

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Royal Society open science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Frontiers in behavioral neuroscience · 2025
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ryley T YostDepartment of Biology, Western University, London, Ontario, Canada.ORCID https://orcid.org/0000-0002-0637-2871
Andrew M ScottSt Joseph's Healthcare, Hamilton, Ontario, Canada.
Judy M KurbajDepartment of Biology, Western University, London, Ontario, Canada.
Brendan Walshe-RousselDepartment of Biology, Western University, London, Ontario, Canada.
Reuven DukasDepartment of Psychology, Neuroscience and Behaviour, Animal Behaviour Group, McMaster University, Hamilton, Ontario, Canada.ORCID https://orcid.org/0000-0003-4533-8542
Anne F SimonDepartment of Biology, Western University, London, Ontario, Canada.ORCID https://orcid.org/0000-0002-6509-4541

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Social isolation causes profound changes in social behaviour in a variety of species. However, the genetic and molecular mechanisms modulating behavioural responses to social isolation and social recovery remain to be elucidated. Here, we quantified the behavioural response of vinegar flies to social isolation using two distinct protocols (social space preference and sociability, the spontaneous tendencies to form groups). We found that social isolation increased social space and reduced sociability. These effects of social isolation were reversible and could be reduced after 3 days of group housing. Flies with a loss of function of

Indexed as

dopamineneuroliginrecoverysocial behavioursocial isolationsocial space

Identifiers

PMID39086833
PMCPMC11288677

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.