Evidence map›Paper›PMID 39087267›Full record

ArticleACS infectious diseases2024

Enhancing the Intrinsic Antiplasmodial Activity and Improving the Stability and Selectivity of a Tunable Peptide Scaffold Derived from Human Platelet Factor 4.

Nicole Lawrence, Thomas N G Handley, Simon J de Veer, Maxim D Harding, Alicja Andraszek, Lachlan Hall, Karoline D Raven, Sandra Duffy, Vicky M Avery, David J Craik and 2 more

Abstract read
In one paragraph

Article in ACS infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Nicole LawrenceInstitute for Molecular Bioscience and Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, The University of Queensland, Brisbane, Queensland 4072, Australia.ORCID 0000-0002-9013-1770
Thomas N G HandleyDepartment of Radiopharmaceutical Sciences, Cancer Imaging, The Peter MacCallum Cancer Centre, Victoria 3000, Australia.
Simon J de VeerInstitute for Molecular Bioscience and Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, The University of Queensland, Brisbane, Queensland 4072, Australia.ORCID 0000-0002-7041-9937
Maxim D HardingInstitute for Molecular Bioscience and Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, The University of Queensland, Brisbane, Queensland 4072, Australia.
Alicja AndraszekInstitute for Molecular Bioscience and Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, The University of Queensland, Brisbane, Queensland 4072, Australia.
Lachlan HallInstitute for Molecular Bioscience and Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, The University of Queensland, Brisbane, Queensland 4072, Australia.ORCID 0009-0001-8177-0247
Karoline D RavenThe John Curtin School of Medical Research, College of Health and Medicine, Australian National University, Canberra, Australian Capital Territory 2601, Australia.ORCID 0000-0002-7579-9721
Sandra DuffyDiscovery Biology, Centre for Cellular Phenomics, School of Environment and Science, Griffith University, Nathan, Queensland 4111, Australia.
Vicky M AveryDiscovery Biology, Centre for Cellular Phenomics, School of Environment and Science, Griffith University, Nathan, Queensland 4111, Australia.
David J CraikInstitute for Molecular Bioscience and Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, The University of Queensland, Brisbane, Queensland 4072, Australia.ORCID 0000-0003-0007-6796
Lara R MalinsResearch School of Chemistry and Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, Australian National University, Canberra, Australian Capital Territory 2601, Australia.ORCID 0000-0002-7691-6432
Brendan J McMorranThe John Curtin School of Medical Research, College of Health and Medicine, Australian National University, Canberra, Australian Capital Territory 2601, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The control of malaria, a disease caused by

Indexed as

AntimalarialsPeptidesPlasmodium falciparumPlatelet Factor 4HumansStructure-Activity RelationshipAntimalarialsPeptidesPlatelet Factor 4drug developmenthost defense peptidemalariaPlasmodiumrational designtargeted cell-penetration

Identifiers

PMID39087267
PMCPMC11320574

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.