Evidence map›Paper›PMID 39089885›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2024

Synchronized Photoactivation of T4K Rhodopsin Causes a Chromophore-Dependent Retinal Degeneration That Is Moderated by Interaction with Phototransduction Cascade Components.

Beatrice M Tam, Paloma Burns, Colette N Chiu, Orson L Moritz

Abstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Advances and therapeutic opportunities in visual cycle modulation.Progress in retinal and eye research · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Beatrice M TamDepartment of Ophthalmology & Visual Sciences, University of British Columbia, Vancouver, British Columbia V5Z 3N9, Canada.
Paloma BurnsDepartment of Ophthalmology & Visual Sciences, University of British Columbia, Vancouver, British Columbia V5Z 3N9, Canada.
Colette N ChiuDepartment of Ophthalmology & Visual Sciences, University of British Columbia, Vancouver, British Columbia V5Z 3N9, Canada.
Orson L MoritzDepartment of Ophthalmology & Visual Sciences, University of British Columbia, Vancouver, British Columbia V5Z 3N9, Canada olmoritz@mail.ubc.ca.ORCID 0000-0002-6183-6499

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple mutations in the

Indexed as

Retinal DegenerationRhodopsinXenopus laevisAnimalsCell Deathcis-trans-IsomerasesFemaleLightLight Signal TransductionMaleRetinal Rod Photoreceptor CellsRetinoid Isomerohydrolasecis-trans-IsomerasesRetinoid IsomerohydrolaseRhodopsinarrestinlightretinitis pigmentosarhodopsinrpe65transducin

Identifiers

PMID39089885
PMCPMC11376340

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.