Evidence map›Paper›PMID 39092061›Full record

ArticlePakistan journal of medical sciences2024

Clinical value of Vitamin-D combined with budesonide/formoterol and theophylline sodium glycinate sustained-release tablets in the treatment of chronic obstructive pulmonary disease patients.

Xiuyuan Ni, Shigeng Zhou, Congling Wang, Shengheng Chen, Jingdan Hu, Shengjing Zhang

Abstract read
In one paragraph

Article in Pakistan journal of medical sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiuyuan NiXiuyuan Ni Department of Respiratory, Wenzhou Geriatric Hospital, Wenzhou city, Zhejiang Province 325000, P.R. China.
Shigeng ZhouShigeng Zhou Department of Respiratory, Wenzhou Geriatric Hospital, Wenzhou city, Zhejiang Province 325000, P.R. China.
Congling WangCongling Wang Department of Respiratory, Wenzhou Geriatric Hospital, Wenzhou city, Zhejiang Province 325000, P.R. China.
Shengheng ChenShengheng Chen Department of Respiratory, Wenzhou Geriatric Hospital, Wenzhou city, Zhejiang Province 325000, P.R. China.
Jingdan HuJingdan Hu Department of Respiratory, Wenzhou Geriatric Hospital, Wenzhou city, Zhejiang Province 325000, P.R. China.
Shengjing ZhangShengjing Zhang Department of Geriatric, Zhejiang Chinese Medical University, Affiliated Wenzhou Hospital of Traditional Chinese Medicine, 9 Jiaowei Street, Wenzhou City, Zhejiang Province 325000, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To explore the clinical value of Vitamin-D combined with budesonide/formoterol (BF) and theophylline sodium glycinate (TSG) sustained-release tablets in the treatment of patients with chronic obstructive pulmonary disease (COPD). Methods: Medical records of 114 patients with CODP, treated in Wenzhou Geriatric Hospital from October 2020 to February 2023, were retrospectively analyzed. Of them, 59 received treatment with Vitamin-D combined with BF and TSG sustained-release tablets (Group-A), and 55 patients received treatment with BF combined with TSG sustained-release tablets (Group-B). Lung function indicators, blood gas status, inflammatory factors, fractional exhaled nitric oxide (FeNO), and 25-hydroxyvitamin D [25(OH)D] levels before and after the treatment in both groups were collected. Results: After the treatment, lung function indicators, blood gas status, inflammatory factors, FeNO, and 25 (OH) D levels in both groups were significantly improved compared to pretreatment levels, and were significantly better in the Group-A compared to Group-B (P<0.05). Conclusions: The combination of Vitamin-D, BF, and TSG sustained-release tablets can effectively regulate the blood gas status of patients with COPD, improve lung function, regulate FeNO and 25 (OH) D, and effectively downregulate the levels of inflammatory factors, thus reducing the degree of inflammatory response.

Indexed as

Budesonide/formoterolChronic obstructive pulmonary diseaseTheophylline sodium glycinate sustained-release tabletsVitamin-D

Identifiers

PMID39092061
PMCPMC11255827

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.