Evidence map›Paper›PMID 39095097›Full record

ReviewClinics in perinatology2024

Treating Seizures and Improving Newborn Outcomes for Infants with Hypoxic-Ischemic Encephalopathy.

Tayyba Anwar, Regina L Triplett, Afaf Ahmed, Hannah C Glass, Renée A Shellhaas

Abstract readReview
In one paragraph

Review in Clinics in perinatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Observational
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tayyba AnwarDepartment of Neurology, Children's National Hospital, 111 Michigan Avenue Northwest, Washington, DC 20010, USA.
Regina L TriplettDepartment of Neurology, Washington University in St Louis, 1 Brookings Drive, Saint Louis, MO 63130, USA.
Afaf AhmedDivision of Pediatric and Developmental Neurology, Department of Neurology, Washington University in St Louis, 1 Brookings Drive, Saint Louis, MO 63130, USA.
Hannah C GlassDepartment of Neurology, University of California San Francisco, 500 Parnassus Avenue, San Francisco, CA 94143, USA.
Renée A ShellhaasDepartment of Neurology, Washington University in St Louis, MSC 8091-29-12400, 660 South Euclid Avenue, Saint Louis, MO 63110, USA. Electronic address: rshellhaas@wustl.edu.

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Epilepsy and Neurodevelopmental Risk Stratification in Very Preterm Infants with Intraventricular HemorrhageK23NS136762 · NINDS · WASHINGTON UNIVERSITY · PI Regina Triplett · 2024 to 2026
$699k
NCATS NIH HHS UL1 TR002345NINDS NIH HHS K23 NS136762NINDS NIH HHS L40 NS134035
6 · The paper itself

Abstract

Hypoxic-ischemic encephalopathy is the most common cause of neonatal seizures. Continuous electroencephalographic monitoring is recommended given high rates of subclinical seizures. Prompt diagnosis and treatment of seizures may improve neurodevelopmental outcomes. International League Against Epilepsy guidelines indicate that (1) phenobarbital remains the first-line treatment of neonatal seizures and (2) early discontinuation of antiseizure medications following resolution of acute provoked seizures, and prior to discharge home, is recommended. Long-term follow-up of these infants is necessary to screen for postneonatal epilepsy and support neurodevelopment.

Indexed as

AnticonvulsantsElectroencephalographyHypoxia-Ischemia, BrainPhenobarbitalSeizuresHumansInfant, NewbornAnticonvulsantsPhenobarbitalEEGEpilepsyNeurocritical carePhenobarbitalSeizure

Identifiers

PMID39095097
PMCPMC11915494

What Socratic holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.