Evidence map›Paper›PMID 39095537›Full record

Trial reportEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2024

Barbed suture in neck dissection: a randomized clinical study on efficacy, safety and aesthetic outcome.

Johannes Doescher, Benjamin Emmanuel, Jens Greve, Patrick J Schuler, Fabian Sommer, Simon Laban, Johannes Veit, Thomas K Hoffmann

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Reviewing the efficacy, safety and aesthetic outcome of barbed suture use in neck dissection.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Johannes DoescherDepartment of Otorhinolaryngology, Head and Neck Surgery, University Medical Center Ulm, Ulm, Germany. Johannes.doescher@googlemail.com.ORCID http://orcid.org/0000-0001-8997-8387
Benjamin EmmanuelDepartment of Otorhinolaryngology, Head and Neck Surgery, University Medical Center Ulm, Ulm, Germany.
Jens GreveDepartment of Otorhinolaryngology, Head and Neck Surgery, University Medical Center Ulm, Ulm, Germany.
Patrick J SchulerDepartment of Otorhinolaryngology, Head and Neck Surgery, University Medical Center Ulm, Ulm, Germany.
Fabian SommerDepartment of Otorhinolaryngology, Head and Neck Surgery, University Medical Center Ulm, Ulm, Germany.
Simon LabanDepartment of Otorhinolaryngology, Head and Neck Surgery, University Medical Center Ulm, Ulm, Germany.
Johannes VeitDepartment of Otorhinolaryngology, Head and Neck Surgery, University Medical Center Ulm, Ulm, Germany.
Thomas K HoffmannDepartment of Otorhinolaryngology, Head and Neck Surgery, University Medical Center Ulm, Ulm, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe resection of lymph nodes/neck dissection is a typical part of the surgical treatment of head and neck malignancies. The aim of this study was to compare subcutaneous closure using single knotted, braided suture (Vicryl

methodsNeck Lock was a randomized clinical trial at a single tertiary referral center. It was conducted from 2016 till 2022 with a follow-up period of 3 months. Assessment of safety and aesthetic outcome was double-blinded. 68 patients were randomized after application of exclusion criteria. Subcutaneous wound closure was performed in an intrapatient randomized fashion for suture technique. The primary endpoint was the duration of subcutaneous sutures. Wound healing and scar formation were recorded at multiple postoperative intervals as secondary endpoints.

resultsThe median age was 61 years, 89.7% were male. 92.6% suffered from a squamous cell carcinoma. There was a significant difference in median subcutaneous suture time (p = 0.024) between the experimental (6:11 ± 2:30 min) and standard (7:01 ± 2.42 min) arms. There was no significant difference in safety when assessing adverse events (AEs). At least one AE occurred in 14.7% vs. 5.9%, for barbed and smooth sutures respectively (p = 0.16).

conclusionFor neck dissection of head and neck malignancies, subcutaneous wound closure with self-locking sutures offers significant time savings over the single knot technique with similar safety and aesthetic results. TRIAL REGISTRATION INFORMATION: The trial was registered with WHO acknowledged primary registry "German Clinical Trials Register" under the ID DRKS00025831 ( https://drks.de/search/de/trial/DRKS00025831 ).

Indexed as

EstheticsNeck DissectionSuturesSuture TechniquesAdultAgedCarcinoma, Squamous CellCicatrixDouble-Blind MethodFemaleHead and Neck NeoplasmsHumansMaleMiddle AgedPostoperative ComplicationsTreatment OutcomeBarbed sutureCost analysisNeck dissectionSurgical training

Identifiers

PMID39095537
PMCPMC11564391

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.