Evidence mapPaperPMID 39095951Full record

SynthesisJournal of cachexia, sarcopenia and muscle2024

The mortality burden of cachexia or weight loss in patients with colorectal or pancreatic cancer: A systematic literature review.

Richard F Dunne, Jeffrey Crawford, Karen E Smoyer, Thomas D McRae, Michelle I Rossulek, James H Revkin, Lisa C Tarasenko, Philip D Bonomi

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of cachexia, sarcopenia and muscle, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
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  5. Observational
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  13. Review
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  18. Review
  19. Frontiers in nutrition · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Richard F DunneDepartment of Medicine and Wilmot Cancer Institute, Division of Hematology/Oncology, University of Rochester Medical Center, Rochester, New York, USA.ORCID 0000-0001-6608-660X
Jeffrey CrawfordDuke Cancer Institute, Duke University Medical Center, Durham, North Carolina, USA.
Karen E SmoyerEnvision Pharma Group, Fairfield, Connecticut, USA.
Thomas D McRaeDepartment of Internal Medicine, Pfizer Research and Development, Pfizer Inc, New York, New York, USA.
Michelle I RossulekInternal Medicine Research Unit, Pfizer Research and Development, Pfizer Inc, Cambridge, Massachusetts, USA.
James H RevkinInternal Medicine Research Unit, Pfizer Research and Development, Pfizer Inc, Cambridge, Massachusetts, USA.
Lisa C TarasenkoGlobal Medical Affairs, Pfizer Inc, New York, New York, USA.
Philip D BonomiDepartment of Internal Medicine, Division of Hematology, Oncology and Cell Therapy, Rush University Medical Center, Chicago, Illinois, USA.

Funding

Pfizer Inc, New York, NY, USA
6 · The paper itself

Abstract

Cancer-associated cachexia is a multifactorial wasting disorder characterized by anorexia, unintentional weight loss (skeletal muscle mass with or without loss of fat mass), progressive functional impairment, and poor prognosis. This systematic literature review (SLR) examined the relationship between cachexia and survival in patients with colorectal or pancreatic cancer in recent literature. The SLR was conducted following PRISMA guidelines. Embase

Indexed as

CachexiaColorectal NeoplasmsPancreatic NeoplasmsWeight LossHumansPrognosisCachexiaColorectal cancerMuscle wastingPancreatic cancerSystematic literature reviewWeight loss

Identifiers

PMID39095951
PMCPMC11446707

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.