Evidence map›Paper›PMID 39096858›Full record

ArticleClinics (Sao Paulo, Brazil)2024

Ablation of myocardial autonomic ganglion plexus in the treatment of bradyarrhythmia A one-arm interventional study.

Mingliang Shao, Chenhuan Yao, Yafan Han, Xianhui Zhou, Yanmei Lu, Ling Zhang, Yaodong Li, Baopeng Tang

Abstract read
In one paragraph

Article in Clinics (Sao Paulo, Brazil), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Mingliang ShaoDepartment of Cardiovascular, The People's Hospital of Xuancheng City, Xuancheng City, Anhui Province, China; Department of Pacing Electrophysiology, Xinjiang Key Laboratory of Electrophysiology and Cardiac Remodeling, The First Affiliated Hospital of Xinjiang Medical University, Urumqi City, Xinjiang Uygur Autonomous Region, China.
Chenhuan YaoDepartment of Research and Teaching, The People's Hospital of Xuancheng City, Xuancheng City, Anhui Province, China.
Yafan HanDepartment of Pacing Electrophysiology, Xinjiang Key Laboratory of Electrophysiology and Cardiac Remodeling, The First Affiliated Hospital of Xinjiang Medical University, Urumqi City, Xinjiang Uygur Autonomous Region, China.
Xianhui ZhouDepartment of Pacing Electrophysiology, Xinjiang Key Laboratory of Electrophysiology and Cardiac Remodeling, The First Affiliated Hospital of Xinjiang Medical University, Urumqi City, Xinjiang Uygur Autonomous Region, China.
Yanmei LuDepartment of Pacing Electrophysiology, Xinjiang Key Laboratory of Electrophysiology and Cardiac Remodeling, The First Affiliated Hospital of Xinjiang Medical University, Urumqi City, Xinjiang Uygur Autonomous Region, China.
Ling ZhangDepartment of Pacing Electrophysiology, Xinjiang Key Laboratory of Electrophysiology and Cardiac Remodeling, The First Affiliated Hospital of Xinjiang Medical University, Urumqi City, Xinjiang Uygur Autonomous Region, China.
Yaodong LiDepartment of Pacing Electrophysiology, Xinjiang Key Laboratory of Electrophysiology and Cardiac Remodeling, The First Affiliated Hospital of Xinjiang Medical University, Urumqi City, Xinjiang Uygur Autonomous Region, China.
Baopeng TangDepartment of Pacing Electrophysiology, Xinjiang Key Laboratory of Electrophysiology and Cardiac Remodeling, The First Affiliated Hospital of Xinjiang Medical University, Urumqi City, Xinjiang Uygur Autonomous Region, China. Electronic address: tangbaopeng1111@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo study the complications and effectiveness of the treatment of chronic arrhythmias with cardiac Ganglion Plexus (GP) ablation, and to explore the value of the treatment of chronic arrhythmias with GP ablation.

methodsThis study was a one-arm interventional study of patients from the first hospital of Xinjiang Medical University and the People's Hospital of Xuancheng City admitted (09/2018-08/2021) because of bradyarrhythmia. The left atrium was modeled using the Carto3 mapping system. The ablation endpoint was the absence of a vagal response under anatomically localized and high-frequency stimulation guidance. Postoperative routine follow-up was conducted. Holter data at 3-, 6-, and 12-months were recorded.

resultsFifty patients (25 male, mean age 33.16 ± 7.89 years) were induced vagal response by either LSGP, LIGP, RAGP, or RIGP. The heart rate was stable at 76 bpm, SNRT 1.092s. DC, DR, HR, SDNN, RMSSD values were lower than that before ablation. AC, SSR, TH values were higher than those before ablation, mean heart rate and the slowest heart rate were significantly increased. There were significant differences in follow-up data between the preoperative and postoperative periods (all p < 0.05). All the patients were successfully ablated, and their blood pressure decreased significantly. No complications such as vascular damage, vascular embolism and pericardial effusion occurred.

conclusionsLeft Atrial GP ablation has good long-term clinical results and can be used as a treatment option for patients with bradyarrhythmia.

Indexed as

BradycardiaCatheter AblationGanglia, AutonomicAdultElectrocardiography, AmbulatoryFemaleHeart AtriaHeart RateHumansMaleMiddle AgedTreatment OutcomeYoung Adult3D mappingAblationBradyarrhythmiaGanglion plexusInterventional study

Identifiers

PMID39096858
PMCPMC11334784

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.