Evidence map›Paper›PMID 39097865›Full record

ArticleIslets2024

Human research islet cell culture outcomes at the Alberta Diabetes Institute IsletCore.

James G Lyon, Alice Lj Carr, Nancy P Smith, Braulio Marfil-Garza, Aliya F Spigelman, Austin Bautista, Doug O'Gorman, Tatsuya Kin, Am James Shapiro, Peter A Senior and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Islets, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

James G LyonAlberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.
Alice Lj CarrAlberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.
Nancy P SmithAlberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.
Braulio Marfil-GarzaAlberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.
Aliya F SpigelmanAlberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.
Austin BautistaAlberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.
Doug O'GormanClinical Islet Transplant Program, University of Alberta, Edmonton, Canada.
Tatsuya KinAlberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.
Am James ShapiroAlberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.
Peter A SeniorAlberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.
Patrick E MacDonaldAlberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human islets from deceased organ donors have made important contributions to our understanding of pancreatic endocrine function and continue to be an important resource for research studies aimed at understanding, treating, and preventing diabetes. Understanding the impacts of isolation and culture upon the yield of human islets for research is important for planning research studies and islet distribution to distant laboratories. Here, we examine islet isolation and cell culture outcomes at the Alberta Diabetes Institute (ADI) IsletCore (

Indexed as

Cell Culture TechniquesIslets of LangerhansAdolescentAdultAgedAlbertaCells, CulturedCell SeparationFemaleHumansIslets of Langerhans TransplantationMaleMiddle AgedYoung Adultbiobankingcell cultureHumaninsulinisletsecretion

Identifiers

PMID39097865
PMCPMC11299626

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.