Evidence map›Paper›PMID 39099796›Full record

ReviewInternational journal of nanomedicine2024

Bioactive Materials That Promote the Homing of Endogenous Mesenchymal Stem Cells to Improve Wound Healing.

Ziwei Jiang, Lianglong Chen, Lei Huang, Shengxiang Yu, Jiabao Lin, Mengyao Li, Yanbin Gao, Lei Yang

Abstract readReview
In one paragraph

Review in International journal of nanomedicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Article
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  6. Review
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  9. Review
  10. Article
  11. Review
  12. Acid-Triggered Dual-Functional Hydrogel Platform for Enhanced Bone Regeneration.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ziwei Jiang *Department of Burns, Nanfang Hospital, Southern Medical University, Guangzhou, People's Republic of China.
Lianglong Chen *Department of Burns, Nanfang Hospital, Southern Medical University, Guangzhou, People's Republic of China.
Lei HuangDepartment of Burns, Nanfang Hospital, Southern Medical University, Guangzhou, People's Republic of China.
Shengxiang YuDepartment of Burns, Nanfang Hospital, Southern Medical University, Guangzhou, People's Republic of China.
Jiabao LinDepartment of Burns, Nanfang Hospital, Southern Medical University, Guangzhou, People's Republic of China.
Mengyao LiDepartment of Burns, Nanfang Hospital, Southern Medical University, Guangzhou, People's Republic of China.ORCID 0000-0003-0490-2178
Yanbin GaoDepartment of Burns, Nanfang Hospital, Southern Medical University, Guangzhou, People's Republic of China.
Lei YangDepartment of Burns, Nanfang Hospital, Southern Medical University, Guangzhou, People's Republic of China.ORCID 0000-0003-0259-2479

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endogenous stem cell homing refers to the transport of endogenous mesenchymal stem cells (MSCs) to damaged tissue. The paradigm of using well-designed biomaterials to induce resident stem cells to home in to the injured site while coordinating their behavior and function to promote tissue regeneration is known as endogenous regenerative medicine (ERM). ERM is a promising new avenue in regenerative therapy research, and it involves the mobilizing of endogenous stem cells for homing as the principal means through which to achieve it. Comprehending how mesenchymal stem cells home in and grasp the influencing factors of mesenchymal stem cell homing is essential for the understanding and design of tissue engineering. This review summarizes the process of MSC homing, the factors influencing the homing process, analyses endogenous stem cell homing studies of interest in the field of skin tissue repair, explores the integration of endogenous homing promotion strategies with cellular therapies and details tissue engineering strategies that can be used to modulate endogenous homing of stem cells. In addition to providing more systematic theories and ideas for improved materials for endogenous tissue repair, this review provides new perspectives to explore the complex process of tissue remodeling to enhance the rational design of biomaterial scaffolds and guide tissue regeneration strategies.

Indexed as

Biocompatible MaterialsMesenchymal Stem CellsTissue EngineeringWound HealingAnimalsCell MovementHumansMesenchymal Stem Cell TransplantationRegenerative MedicineSkinTissue ScaffoldsBiocompatible Materialsbioactive materialsbiomimetic designendogenous stem cell homingin situ tissue regenerationwound healing

Identifiers

PMID39099796
PMCPMC11297574

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.