Evidence map›Paper›PMID 39102111›Full record

Trial reportEndocrine2025

Effect of an intensive nutrition intervention of a high protein and low glycemic load diet on weight of kidney transplant recipients: a randomized clinical trial.

Elis Forcellini Pedrollo, Camila Corrêa, Bruna Bellincanta Nicoletto, Júlia de Melo Cardoso de Freitas, Júlia Roberta Buboltz, Beatriz Dorneles Ferreira da Costa, Gabriela Dos Santos Guedes, Andrea Carla Bauer, Roberto Ceratti Manfro, Gabriela Corrêa Souza and 1 more

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Endocrine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02883777 (Effect of a High Protein and Low Glycemic Index Diet on Kidney Transplant), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02883777 naunknown statusnot on this map

Effect of a High Protein and Low Glycemic Index Diet on Kidney Transplant

TypeinterventionalSponsorHospital de Clinicas de Porto AlegreRan2016 to 2018Enrolled120ConditionsKidney Failure, Chronic, End-Stage Renal DiseaseArmsHigh Protein and Low Glycemic Index Diet, Conventional Diet
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Elis Forcellini PedrolloPrograma de Pós-Graduação em Ciências Médicas, Endocrinologia, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil. elispedrollo@gmail.com.
Camila CorrêaPrograma de Pós-Graduação em Ciências Médicas, Endocrinologia, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Bruna Bellincanta NicolettoÁrea de Conhecimento de Ciências da Vida, Universidade de Caxias do Sul, Caxias do Sul, Brazil.
Júlia de Melo Cardoso de FreitasDepartamento de Nutrição, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Júlia Roberta BuboltzDepartamento de Nutrição, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Beatriz Dorneles Ferreira da CostaDepartamento de Nutrição, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Gabriela Dos Santos GuedesDepartamento de Nutrição, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Andrea Carla BauerPrograma de Pós-Graduação em Ciências Médicas, Endocrinologia, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Roberto Ceratti ManfroDepartamento de Medicina Interna, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Gabriela Corrêa SouzaDepartamento de Nutrição, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Cristiane Bauermann LeitãoPrograma de Pós-Graduação em Ciências Médicas, Endocrinologia, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this study is to evaluate the effect of a high protein and low glycemic load diet in preventing weight gain after kidney transplantation.

methodsWe designed a prospective, single-center, open-label, randomized controlled study to compare the efficacy of a high protein (1.3-1.4 g/kg/day) and low glycemic load diet versus a conventional diet (0.8-1.0 g/kg/day of protein and no recommendations on glycemic load) in preventing weight gain (ClinicalTrials.gov identifier: NCT02883777). A total of 120 patients were evaluated. Patients were followed for 12 months, and the primary outcome was weight maintenance or weight gain lower than 5%.

resultsThere were no differences in total energy intake, carbohydrates, and total fats between groups. Intervention group (IG) increased protein intake to 1.38 ± 0.56 g/kg/day and decreased the glycemic load to 87.27 ± 4.54 g/day, while control group (CG) had a dietary protein intake of 1.19 ± 0.43 g/kg/day and a glycemic load of 115.60 ± 7.01 g/day. Total fiber intake was greater and trans-fat was lower in IG. Dietetic cholesterol increased in IG over time and was significantly different between groups. Overall, patients had an increase in body weight over time, with a mean increment of 4.1 ± 5.5 kg (5.75%). The percentage of patients who achieved the primary outcome was 50% of sample size, without differences between groups. The glomerular filtration rate improved over time in both groups. Considering 24-h proteinuria and albuminuria, a similar rise was observed in both groups.

conclusionThe present dietary intervention was safe, but had no effect on weight gain in kidney transplant subjects. Our findings suggest that other strategies, including alternative dietary and/or pharmacological and psychological interventions might be tested in randomized control trials in order to improve patients' body weight outcomes after transplant.

Indexed as

Dietary ProteinsDiet, High-ProteinGlycemic LoadKidney TransplantationWeight GainAdultAgedFemaleHumansMaleMiddle AgedProspective StudiesDietary ProteinsHigh protein dietKidney transplantationLow glycemic load dietNutrition interventionWeight

Identifiers

PMID39102111

What Socratic holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.