Evidence map›Paper›PMID 39103464›Full record

ArticleScientific reports2024

Serum levels of biomarkers related to severity staging of Raynaud's phenomenon, neurosensory manifestations, and vibration exposure in patients with hand-arm vibration injury.

Eva Tekavec, Tohr Nilsson, Lars B Dahlin, Elizabeth Huynh, Catarina Nordander, Jakob Riddar, Monica Kåredal

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Eva TekavecDivision of Occupational and Environmental Medicine, Department of Laboratory Medicine, Lund University, 221 00, Lund, Sweden. eva.tekavec@med.lu.se.
Tohr NilssonDivision of Sustainable Health and Medicine, Department of Public Health and Clinical Medicine, Umeå University, 901 87, Umeå, Sweden.
Lars B DahlinDepartment of Translational Medicine - Hand Surgery, Lund University, 221 00, Lund, Sweden.
Elizabeth HuynhDepartment of Occupational and Environmental Medicine, Region Skåne, 223 63, Lund, Sweden.
Catarina NordanderDivision of Occupational and Environmental Medicine, Department of Laboratory Medicine, Lund University, 221 00, Lund, Sweden.
Jakob RiddarDivision of Occupational and Environmental Medicine, Department of Laboratory Medicine, Lund University, 221 00, Lund, Sweden.
Monica KåredalDivision of Occupational and Environmental Medicine, Department of Laboratory Medicine, Lund University, 221 00, Lund, Sweden.

Funding

AFA Insurance 170124Swedish Research Council 2022-01942The Swedish Diabetes Foundation DIA2020-492
6 · The paper itself

Abstract

Our aim was to explore possible relationships between serum levels of biomarkers in patients with hand-arm vibration injury in relation to the severity of the vascular, i.e., Raynaud's phenomenon (RP), and neurosensory manifestations, the current exposure level, and the duration of exposure. This study was of case series design and involved 92 patients diagnosed with hand-arm vibration injury. Jonckheere's trend test was used to assess any association between serum levels of biomarkers and RP as well as neurosensory manifestations, graded by the International Consensus Criteria. Generalized linear models with adjustment for possible confounders were also used for associations between serum levels of biomarkers and; (1) severity of RP recorded as the extent of finger blanching calculated with Griffin score, (2) vibration perception thresholds, (3) magnitude of current exposure as [A(8); (m/s

Indexed as

BiomarkersHand-Arm Vibration SyndromeRaynaud DiseaseVibrationAdultAgedCalcitonin Gene-Related PeptideFemaleHumansMaleMiddle AgedSeverity of Illness Indexvon Willebrand FactorBiomarkersCalcitonin Gene-Related Peptidevon Willebrand FactorAβ fibersAδ fibersC-fibersCold intoleranceEndothelial dysfunctionGrading of injuryHand-arm vibration syndrome (HAVS)NeuroprotectionOccupationalSerum biomarkersVibration exposure

Identifiers

PMID39103464
PMCPMC11300662

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.