Evidence map›Paper›PMID 39103488›Full record

ArticleScientific reports2024

Continuous sepsis trajectory prediction using tensor-reduced physiological signals.

Olivia P Alge, Joshua Pickard, Winston Zhang, Shuyang Cheng, Harm Derksen, Gilbert S Omenn, Jonathan Gryak, J Scott VanEpps, Kayvan Najarian

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Olivia P AlgeDepartment of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA. oialge@umich.edu.
Joshua PickardDepartment of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.
Winston ZhangDepartment of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.
Shuyang ChengDepartment of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.
Harm DerksenDepartment of Mathematics, Northeastern University, Boston, MA, USA.
Gilbert S OmennDepartment of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.
Jonathan GryakDepartment of Computer Science, Queens College, CUNY, Queens, NY, USA.
J Scott VanEppsMichigan Center for Integrative Research in Critical Care, University of Michigan, Ann Arbor, MI, USA.
Kayvan NajarianDepartment of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.

Funding

Strategic Vision & Impact on Environmental HealthP30ES017885 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Dana Dolinoy · 2011 to 2026
$21.3M
Training Program in BioinformaticsT32GM070449 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ATHEY, BRIAN DAVID, BURMEISTER, MARGIT · 2005 to 2020
$3.6M
National Science Foundation 1837985NIEHS NIH HHS P30 ES017885NIH HHS 3-P30-ES-017885-11-S1NIH HHS T32GM070449
6 · The paper itself

Abstract

The quick Sequential Organ Failure Assessment (qSOFA) system identifies an individual's risk to progress to poor sepsis-related outcomes using minimal variables. We used Support Vector Machine, Learning Using Concave and Convex Kernels, and Random Forest to predict an increase in qSOFA score using electronic health record (EHR) data, electrocardiograms (ECG), and arterial line signals. We structured physiological signals data in a tensor format and used Canonical Polyadic/Parallel Factors (CP) decomposition for feature reduction. Random Forests trained on ECG data show improved performance after tensor decomposition for predictions in a 6-h time frame (AUROC 0.67 ± 0.06 compared to 0.57 ± 0.08,

Indexed as

ElectrocardiographySepsisAgedElectronic Health RecordsFemaleHumansMaleMiddle AgedOrgan Dysfunction ScoresSupport Vector Machine

Identifiers

PMID39103488
PMCPMC11300462

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.