Evidence map›Paper›PMID 39104728›Full record

ReviewAsia-Pacific journal of oncology nursing2024

Review of the microbiome and metabolic pathways associated with psychoneurological symptoms in children with cancer.

Caitlin I Webster, Janice S Withycombe, Jessica Sheth Bhutada, Jinbing Bai

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Asia-Pacific journal of oncology nursing, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Caitlin I WebsterNell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA, USA.
Janice S WithycombeClemson University School of Nursing, Clemson University, Clemson, SC, USA.
Jessica Sheth BhutadaCancer and Blood Disease Institute, Children's Hospital Los Angeles, Los Angeles, CA, USA.
Jinbing BaiNell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA, USA.

Funding

Exploring the Microbiome-Gut-Brain Axis in Psychoneurological Symptoms for Children with Solid TumorsR00NR017897 · NINR · EMORY UNIVERSITY · PI BAI, JINBING · 2020 to 2022
$736k
Exploring the Microbiome-Gut-Brain Axis in Psychoneurological Symptoms for Children with Solid TumorsK99NR017897 · NINR · EMORY UNIVERSITY · PI BAI, JINBING · 2018 to 2019
$181k
NINR NIH HHS K99 NR017897NINR NIH HHS R00 NR017897
6 · The paper itself

Abstract

Children with cancer often endure a range of psychoneurological symptoms (PNS), including pain, fatigue, cognitive impairment, anxiety, depressive symptoms, and sleep disturbance. Despite their prevalence, the underlying pathophysiology of PNS remains unclear. Hypotheses suggest an interplay between the gut microbiome and the functional metabolome, given the immune, neurological, and inflammatory influences these processes exert. This mini-review aims to provide a synopsis of the literature that examines the relationship between microbiome-metabolome pathways and PNS in children with cancer, drawing insights from the adult population when applicable. While there is limited microbiome research in the pediatric population, promising results in adult cancer patients include an association between lower microbial diversity and compositional changes, including decreased abundance of the beneficial microbes

Indexed as

MetabolomeMicrobiomeMulti-omicsPediatric oncologyPsychoneurological symptoms

Identifiers

PMID39104728
PMCPMC11298867

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.