Evidence map›Paper›PMID 39105209›Full record

ArticleJournal of Taibah University Medical Sciences2024

Alex Boye, Victor A Barku, Justice K Addo, Orleans Martey, Ernest A Asiamah, Mainprice A Essuman, Dennis Doe

Abstract read
In one paragraph

Article in Journal of Taibah University Medical Sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alex BoyeDepartment of Medical Laboratory Science, School of Allied Health Sciences, College of Health and Allied Sciences, University of Cape Coast, Cape Coast, Ghana.
Victor A BarkuDepartment of Chemistry, School of Physical Sciences, University of Cape Coast, Cape Coast, Ghana.
Justice K AddoDepartment of Chemistry, School of Physical Sciences, University of Cape Coast, Cape Coast, Ghana.
Orleans MarteyDepartment of Pharmacology, Center for Plant Medicine Research, Mampong-Akuapem, Ghana.
Ernest A AsiamahDepartment of Chemistry, School of Physical Sciences, College of Agriculture and Natural Sciences, University of Cape Coast, Ghana.
Mainprice A EssumanDepartment of Medical Laboratory Science, School of Allied Health Sciences, College of Health and Allied Sciences, University of Cape Coast, Cape Coast, Ghana.
Dennis DoeDepartment of Medical Laboratory Science, School of Allied Health Sciences, College of Health and Allied Sciences, University of Cape Coast, Cape Coast, Ghana.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study assessed the prophylactic anti-HCC effects of a combined stem and root alkaloidal extract of Methods: SRAEZZ was prepared from dried stems and roots of Results: SRAEZZ yield was 0.58% from the initial stem and root sample (520 g). Quaternary phenanthridin alkaloids were detected in SRAEZZ. Control rats had a 100% survival rate compared with rats in the model group. SRAEZZ treatment improved the survival rate with respect to that in the model group. Serum AFP, CRP, and bilirubin levels were greater in the model group than the control group. SRAEZZ decreased serum AFP, CRP, and bilirubin below the levels observed in the model group. ALP, AST, and AST were higher in the model group, but lower in SRAEZZ-treated group, than the control group. Conclusion: SRAEZZ demonstrated prophylactic anti-HCC effects against CCl

Indexed as

Alpha (α)-fetoproteinCarbon tetrachlorideC-reactive proteinHCCQuaternary phenanthridin alkaloidsZ. zanthoxyloides

Identifiers

PMID39105209
PMCPMC11298919

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.