ArticleJournal of diabetes investigation2024
Coexistence of high visceral fat area and sarcopenia is associated with atherosclerotic markers in old-old patients with diabetes: A cross-sectional study.
Article in Journal of diabetes investigation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Sarcopenia in type 2 Diabetes mellitus among Asian populations: prevalence and risk factors based on AWGS- 2019: a systematic review and meta-analysis.BMC endocrine disorders · 2025Pooled it
- Visceral Adiposity, Rather than Reduced Appendicular Lean Mass, Characterizes Elderly Hip Fracture Patients with Type 2 Diabetes: A Cross-Sectional DXA Analysis.Journal of clinical medicine · 2026Article
- One-year body weight loss and gain as independent predictors of frailty-related outcomes and mortality in an aging Japanese population.Scientific reports · 2026Article
- Association Between Waist Circumference and Coronary Artery Disease: Evidence from the NHANES 1999-2023 Cross-Sectional Data and Mendelian Randomization Analysis.Global heart · 2026Article
- Research Progress on the Association Between Sarcopenic Obesity and Atherosclerosis: Current Status and Challenges.Journal of clinical medicine · 2025Review
- Reply to the comments of Saleh et al. on "Coexistence of high visceral fat area and sarcopenia and atherosclerotic markers in old-old patients with diabetes: Is there an association?"Journal of diabetes investigation · 2025Article
- Metabolomics and Gut Microbiota in Elderly Patients with Diabetic Peripheral Neuropathy and Sarcopenia.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Article
- Association between sarcopenic obesity and cardiovascular diseases: the role of systemic inflammation indices.Frontiers in medicine · 2025Article
- Coexistence of high visceral fat area and sarcopenia and atherosclerotic markers in older patients with diabetes: Is there an association?Journal of diabetes investigation · 2024Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
AIMS/
introductionTo investigate whether sarcopenic obesity is associated with the progression of atherosclerotic lesions in older patients with diabetes and to identify the obesity components of sarcopenic obesity that best reflect atherosclerosis. MATERIALS AND
methodsIn 118 inpatients aged ≥75 years with diabetes mellitus, sarcopenia defined as a low skeletal muscle mass and low grip strength was assessed, and sarcopenia coexisting with a high body-fat percentage or visceral fat area was defined as sarcopenic obesity. Correlations between the obesity components and atherosclerotic markers, including the carotid intima-media thickness, were analyzed; the intima-media thickness was analyzed in four groups with and without obesity and sarcopenia, and a multiple linear regression analysis adjusted for covariates was conducted to investigate whether sarcopenic obesity was independently associated with the intima-media thickness.
resultsThe visceral fat area and intima-media thickness showed positive correlations in the overall patients (P = 0.032) and the sarcopenia (P = 0.016) group but showed no associations in participants without sarcopenia. The intima-media thickness in the group showing sarcopenia with a high visceral fat area was significantly higher than that in the control group (P = 0.012). Sarcopenic obesity defined by a high body-fat percentage and high visceral fat area was independently associated with the intima-media thickness even after adjusting for age, sex, and atherogenic risk factors. However, sarcopenic obesity defined by a high visceral fat area was more strongly associated with the intima-media thickness (β = 0.384, P = 0.002) than that defined by the high body-fat percentage (β = 0.237, P = 0.068).
conclusionsSarcopenic obesity, especially that defined by visceral fat accumulation, reflected the risk of atherosclerotic lesion progression in older patients with diabetes.
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