Evidence map›Paper›PMID 39105587›Full record

ArticleMicrobiology spectrum2024

Cyclization increases bactericidal activity of arginine-rich cationic cell-penetrating peptide for

Constance M John, Suzanne A Otala, Gary A Jarvis

Abstract read
In one paragraph

Article in Microbiology spectrum, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Biology of novel LpxC inhibitors forMicrobiology spectrum · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Constance M JohnDepartment of Laboratory Medicine, University of California San Francisco, San Francisco, California, USA.ORCID 0000-0003-4984-6325
Suzanne A OtalaVeterans Affairs Medical Center, San Francisco, California, USA.ORCID 0009-0008-2695-5629
Gary A JarvisDepartment of Laboratory Medicine, University of California San Francisco, San Francisco, California, USA.ORCID 0000-0002-7576-3702

Funding

Targeting of LOS for Treatment of Antibiotic-Resistant Neisseria gonorrhoeaeI01BX000727 · VA · VETERANS AFFAIRS MED CTR SAN FRANCISCO · PI JARVIS, GARY A · 2011 to 2025
–
BLRD VA I01 BX000727BLRD VA IK6 BX005798U.S. Department of Veterans Affairs (VA) BX000727
6 · The paper itself

Abstract

We previously reported that a linear cationic 12-amino acid cell-penetrating peptide (CPP) was bactericidal for

Indexed as

Anti-Bacterial AgentsCell-Penetrating PeptidesGonorrheaNeisseria gonorrhoeaeAnimalsArginineBiofilmsCyclizationFemaleHumansLipopolysaccharidesMiceMicrobial Sensitivity TestsAnti-Bacterial AgentsArginineCell-Penetrating Peptideslipid-linked oligosaccharidesLipopolysaccharidesbactericidal activitycell-penetrating peptidesgonorrhealipooligosaccharideNeisseria gonorrhoeaesialic acid

Identifiers

PMID39105587
PMCPMC11370255

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.