Evidence map›Paper›PMID 39106091›Full record

ArticleExperimental physiology2024

Somatosensory processing in long COVID fatigue and its relations with physiological and psychological factors.

Bethan Thomas, Rachael Pattinson, Christine Bundy, Jennifer L Davies

Abstract read
In one paragraph

Article in Experimental physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Bethan ThomasSchool of Healthcare Sciences, Cardiff University, Cardiff, UK.ORCID https://orcid.org/0009-0002-0294-6839
Rachael PattinsonSchool of Dentistry, Cardiff University, Cardiff, UK.ORCID https://orcid.org/0000-0002-3145-3710
Christine BundySchool of Healthcare Sciences, Cardiff University, Cardiff, UK.ORCID https://orcid.org/0000-0002-5981-3984
Jennifer L DaviesSchool of Healthcare Sciences, Cardiff University, Cardiff, UK.ORCID https://orcid.org/0000-0001-7635-4815

Funding

HCRW_ HS 22 33
6 · The paper itself

Abstract

Fatigue is prevalent amongst people with long COVID, but is poorly understood. The sensory attenuation framework proposes that impairments in sensory processing lead to heightened perception of effort, driving fatigue. This study aims to investigate the role of somatosensory processing impairments in long COVID fatigue and quantify how sensory processing relates to other prominent symptoms of long COVID including autonomic dysfunction, mood and illness beliefs in driving the experience of fatigue. We will recruit 44 individuals with long COVID fatigue and 44 individuals with neither long COVID nor fatigue (controls). Our primary objective is to compare baseline somatosensory processing between individuals with long COVID fatigue and controls. Additionally, we will explore the associations between somatosensory processing, fatigability and the level of fatigue induced by cognitive and physical exertion. Due to the complex nature of fatigue, we will also investigate how long COVID, state fatigue, perceived effort, mood, illness beliefs, autonomic symptoms and autonomic nervous system function interact to predict trait fatigue. This comprehensive investigation aims to elucidate how sensory processing and other prominent symptoms interact to impact the experience of fatigue.

Indexed as

COVID-19FatigueAdultAffectAutonomic Nervous SystemFemaleHumansMaleMiddle AgedPhysical ExertionSARS-CoV-2autonomic nervous systemfatiguelong COVIDphysiologypsychologysensory processingsomatosensory system

Identifiers

PMID39106091
PMCPMC11442760

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.