Evidence map›Paper›PMID 39109910›Full record

ArticlePediatric pulmonology2024

Postnatal chest X-ray in children with asymptomatic congenital lung malformations.

Louis W J Dossche, Charlotte S van den Aardwegh, Casper M Kersten, Joost van Rosmalen, Rene M H Wijnen, Hanneke IJsselstijn, J Marco Schnater

Abstract read
In one paragraph

Article in Pediatric pulmonology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Louis W J DosscheDepartment of Pediatric Surgery, Erasmus MC Sophia Children's Hospital, Rotterdam, The Netherlands.ORCID 0009-0003-8432-0414
Charlotte S van den AardweghDepartment of Pediatric Surgery, Erasmus MC Sophia Children's Hospital, Rotterdam, The Netherlands.
Casper M KerstenDepartment of Pediatric Surgery, Erasmus MC Sophia Children's Hospital, Rotterdam, The Netherlands.
Joost van RosmalenDepartment of Biostatistics, Erasmus MC, Rotterdam, The Netherlands.ORCID 0000-0002-9187-244X
Rene M H WijnenDepartment of Pediatric Surgery, Erasmus MC Sophia Children's Hospital, Rotterdam, The Netherlands.
Hanneke IJsselstijnDepartment of Pediatric Surgery, Erasmus MC Sophia Children's Hospital, Rotterdam, The Netherlands.ORCID 0000-0001-5824-3492
J Marco SchnaterDepartment of Pediatric Surgery, Erasmus MC Sophia Children's Hospital, Rotterdam, The Netherlands.ORCID 0000-0003-4910-8293

Funding

This study did not receive any funding from third-party sources
6 · The paper itself

Abstract

objectiveThe clinical implications of a postnatal chest X-ray (CXR) in asymptomatic children with a prenatally diagnosed congenital lung malformation (CLM) are uncertain. We assessed the justification for the postnatal use of CXR in these children.

methodsWe included patients with CLM confirmed through chest computed tomography angiography or histopathological analysis who were asymptomatic at birth, underwent routine postnatal CXR, and participated in our standard of care prospective structured longitudinal follow-up program. Children with major associated morbidities were excluded. Primary outcomes were the positive and negative predictive values (PPV and NPV) of CXR findings for symptom development at 4 weeks and 6 months of age. Secondarily, we sought to establish whether CXR findings were associated with undergoing additional diagnostics during the initial observational hospital stay or prolonged postnatal hospital admission.

resultsAmong 121 included patients, CXR showed no abnormalities in 35 (29%), nonspecific abnormalities in 23 (19%), and probable CLM in 63 (52%). The PPV of CXR in relation to symptom development at 4 weeks and 6 months was 0.05 and 0.25, respectively. Corresponding NPVs were 0.96 and 0.91. An association was identified between CXR findings and undergoing further diagnostics during the initial observational hospital stay (p = .047). Additional diagnostic findings did not influence clinical management. CXR findings were not associated with prolonged initial hospital stay (p = .40).

conclusionThe routine practice of postnatal CXR in asymptomatic patients with prenatally diagnosed CLM can be omitted, as CXR findings do not influence subsequent clinical management.

Indexed as

LungRadiography, ThoracicFemaleHumansInfantInfant, NewbornLongitudinal StudiesMalePredictive Value of TestsProspective StudiesTomography, X-Ray Computedcongenital abnormalitiesdiagnostic imaginglung diseaseradiographyrespiratory system abnormalities

Identifiers

PMID39109910
PMCPMC11601021

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.